Research on Secondary Metabolites and Screening for Nematicidal Activity of the Marine Actinomycete Streptomyces avidinii
Study of the active material basis of killing nematodes by marine actinomycetes.Theliquid fermentation of eighty-one strains of marine Actinomycetes were screened for killing nematode,and then the fermentation liquid of the active strains was separated and purified,furthermore the compounds were screened for nematoidal activity.A marine Actinomycete strain with high nematicidal activity was screened and its nematode mortality rate reached 89.9%.The strain was identified as Streptomyces avidinii,seven compounds were obtained from its fermentation broth,and the compounds were named as pyrrole-2-carboxamide(1),N-(3-(1H-indole-3-yl)propyl)acetamide(2),p-hydroxybenzyl alcohol(3),N-acetyltyramine(4),4-methyl-1-phenylpentane-2,3-diol(5),1H-indole-3-aldehyde(6)and zarzissine(7).Among them,compounds 3 and 4 showed better nematicidal activity.
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