Objective The aim of this study is to fabricate a digital maxillofacial prosthesis using multi-source data modeling and computer-aided design/computer-aided manufacturing(CAD/CAM)and to evaluate its clinical application preliminarily.Methods Digital impressions were obtained by integrating the intraoral optical scanning data with the computed tomography(CT)data.Metal framework,obturator,and artificial teeth were de-signed based on the model data by utilizing dental design software.The definitive prosthesis was manufactured by three-dimensional printing(3DP).Three patients were treated with both the traditional and digital prostheses simul-taneously,with the traditional prosthesis serving as its control group.Silicone rubber lining was used to assess the adaption of the two types of prosthesis(the gap between the prosthesis's tissue surface and the intraoral soft tis-sues).Results The digital fabrication of maxillofacial prosthesis was realized successfully.The adaption of the traditional prosthesis framework and obturator was(294.0±64.4)μm and(357.8±82.4)μm,respectively;and the adaption of digital prosthesis framework and obturator was(364.6±62.6)μm and(345.1±95.5)μm,respectively,which were within the clinically acceptable range,with no statistical difference between the two groups.Conclusion Digital prosthesis is a simple and effective method for maxillofacial defect reconstruction,and its adaption is suitable for clinical application.
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