首页|2022年WHO头颈部肿瘤分类(第5版)的解读:口腔和舌体上皮性肿瘤

2022年WHO头颈部肿瘤分类(第5版)的解读:口腔和舌体上皮性肿瘤

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2022年3月,世界卫生组织(World Health Organization,WHO)发布了第5版《头颈部肿瘤分类》.第5版的口腔和舌体肿瘤部分中,上皮性肿瘤相较于2017年的第4版作出了一些修改,其中包括将口腔潜在恶性疾病(oral potentially malignant disorders,OPMD)和口腔上皮异常增生(oral epithelial dysplasia,OED)作了分开阐述,并详细讨论了黏膜下纤维性变(submucous fibrosis,SF)和人乳头瘤病毒(human papillomavirus,HPV)相关性口腔上皮异常增生(HPV-associated oral epithelial dysplasia,HPVOED);在鳞状细胞癌(squamous cell carcinoma,SCC)部分,介绍了穿掘性癌(carcinoma cuniculatum,CC)和疣状癌(verrucous carcinoma,VC),并阐述了其特有的临床和组织学特征.本文总结了自2017年来口腔和舌体的上皮性肿瘤相关内容在临床、组织学和分子学研究中的最新进展.
Interpretation of the WHO 2022 classification of head and neck tumours(5th Edition):The epithelial tumours of oral cavity and mobile tongue
The 5th edition of the Classification of Head and Neck Tumours by the World Health Organization(WHO)was published in March 2022.In the section on oral cavity and mobile tongue tumours,the classification of epithelial tumours in the 5th edition has undergone several modifications compared to the 4th edition published in 2017.Notably,oral potentially malignant disorders(OPMD)and oral epithelial dysplasia(OED)have been addressed separately,and in-depth discussions have been included regarding submucosal fibrosis(SF)and human papillomavirus(HPV)-associated oral epithelial dysplasia(HPVOED).Additionally,the section on squamous cell carcinoma(SCC)now includes carcinoma cuniculatum(CC)and verrucous carcinoma(VC),emphasizing their distinctive clinical and histological characteristics.This review provides a comprehensive overview of the most recent advancements in clinical,histological,and molecular research on epithelial tumours of oral cavity and mobile tongue since 2017.

World Health Organizationoral cavity and mobile tongue tumoursnon-neoplastic lesionsepithelial tumours

李金薇、沙桐、郑凯娟、聂孟冬、关苇杭、史册

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吉林大学口腔医院口腔病理科,吉林省牙发育及颌骨重塑与再生重点实验室,长春 130021

世界卫生组织 口腔和舌体肿瘤 非肿瘤性病变 上皮性肿瘤

国家自然科学基金国家自然科学基金吉林大学白求恩计划中央高校基本科研业务费专项

82270959819709032023B28

2024

口腔颌面外科杂志
同济大学

口腔颌面外科杂志

CSTPCD
影响因子:0.982
ISSN:1005-4979
年,卷(期):2024.34(2)
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