摘要
机械力刺激对骨代谢的影响受到学者们的广泛关注.随着科学研究的深入,研究的焦点逐渐转向更为细化的层面.学者们试图从多个角度探讨这一问题,包括不同力学性质、力学强度、力的频率、细胞类型及分子机制对骨代谢的影响.近年来研究热点集中于如何通过改变机械力刺激或者针对特定细胞类型及某种感受器来调整骨代谢水平.鉴于这一过程的复杂性,本文旨在综述机械力刺激对骨代谢影响的相关最新研究进展,以期为进一步研究提供参考.
Abstract
The impact of mechanical force stimulation on bone metabolism is currently garnering significant scholarly interest.As scientific inquiry progresses,the focus of these studies has increasingly shifted towards a more granular level of analysis.Recent years,researchers are now examining this phenomenon from various perspectives,including the influence of differing mechanical properties,force magnitudes,frequencies,cell types,and underlying molecular mechanisms on bone metabolism.Given the intricate nature of this process,this article seeks to provide a comprehensive overview of the advancements in research pertaining to the modulation of bone metabolism through the alteration of mechanical stimuli or the targeting of specific cell types and receptors,in order to provide a reference for further research.
基金项目
科技部重点研发专项(2018YFE0202200)
国家自然科学基金(81670962)
同济大学中央高校基本业务费专项(22120180196)
维普
万方数据