Objective:To study the optimal process conditions of preparing porous HAPw-nmZnO-nmCao bone repair materials by adding pore-forming agent.Methods:HAPw-nmZnO-nmCaO colloidal silica and PMMA were used to form porous bone scaffold materials through mould forming and high-temperature calcination.We used XRD,SEM,Archimedes drain method and universal testing machines to characterize the materials.The degradation properties in vitro and cytotoxicity of porous bone repair materials was also discussed.Results:The results showed that when the calcination temperature should be lower than 600℃.The optimum process conditions were as follows:pore-making agent accounting for 20％wt,600℃ of calcination temperature.The porous bone repair materials that we prepared under these conditions have good porosity(47％)and mechanical strength(2.6 MPa),with suitable degradation rate and biocompatibility.Conclusion:This study successfull screened out the optimal process conditions of preparing porous HAPw-nmZnO-nmCao bone repair materials using the method of adding pore forming agent.
维普
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