口腔颌面修复学杂志2024,Vol.25Issue(3) :234-240.DOI:10.19748/j.cn.kqxf.1009-3761.2024.3.014

促牙本质再矿化树脂粘接材料提高牙本质粘接耐久性的研究进展

Research progress of dentin remineralization promoting resin bonding materials to improve the durability of dentin bonding

苗瑞婧 张存宝 张黄 王永武
口腔颌面修复学杂志2024,Vol.25Issue(3) :234-240.DOI:10.19748/j.cn.kqxf.1009-3761.2024.3.014

促牙本质再矿化树脂粘接材料提高牙本质粘接耐久性的研究进展

Research progress of dentin remineralization promoting resin bonding materials to improve the durability of dentin bonding

苗瑞婧 1张存宝 1张黄 1王永武1
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作者信息

  • 1. 杭州市第一人民医院口腔科 杭州市第一人民医院 杭州 310000
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摘要

促进牙本质再矿化是提高树脂-牙本质粘接耐久性的重要方法,国内国际有很多关于改性树脂粘接剂的研究,均致力于诱导混合层裸露牙本质胶原的再矿化.本文针对树脂-牙本质粘接面的耐久性问题,阐述了促牙本质再矿化树脂粘接材料的研究进展.促牙本质再矿化树脂粘接材料的改性策略包括:生物活性无机微填料策略,即以硅酸盐、磷酸钙盐和生物活性玻璃等无机材料为矿化离子来源诱导牙本质再矿化;仿生再矿化策略,即应用仿生类似物模拟非胶原蛋白(non-collagenous proteins,NCPs)的功能,引导矿物前驱体在特定位点矿化以获得与生物矿化类似的有序晶体沉积;以及锌添加剂保护胶原蛋白、介孔硅材料作为矿物离子输送系统的改性策略.

Abstract

Promoting remineralization of dentin is an important method to improve the bonding performance of resin bonding materials.There are many researches on modified resin bonding materials worldwide,all of which are committed to inducing remineralization of the mixed layer of exposed dentin collagen.Aiming at the durability of resin dentin bonding surface,this paper reviewed the research progress of resin modification strategies for remineralizing dentin.The modification strategies of the resin modified materials for dentin remineralization include:bioactive inorganic micro filler strategy,which uses inorganic materials such as silicate,calcium phosphate and bioactive glass as the source of mineralized ions to induce dentin remineralization;biomimetic remineralization strategy,that is,using biomimetic analogues to simulate the function of non collagenous proteins(NCPs),to guide mineral precursors to mineralize at specific sites to obtain ordered crystal deposits similar to biomineralization;zinc additives protect collagen and mesoporous silica as the modification strategy of mineral ion transport system.

关键词

树脂粘接材料/牙本质粘接/牙本质再矿化

Key words

modified resin materials/dentin bonding/dentin remineralization

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基金项目

杭州市卫生科技计划项目(A20200072)

浙江中医药大学教育教学改革研究项目(国际教育专项)(GJ22006)

出版年

2024
口腔颌面修复学杂志
首都医科大学附属北京口腔医院 解放军总医院

口腔颌面修复学杂志

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影响因子:0.893
ISSN:1009-3761
参考文献量6
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