Objective:To investigate the clinical effect of sticky bone preservation in alveolar ridge site of molars.Methods:Patients with single first or second molar requiring site preservation after extraction from Huizhou Stomatological Hospital from January 1,2022 to December 31,2022 were selected as study objects and grouped using random number table method.The experimental group was filled with sticky bone(25 cases),and the control group was filled with concentrated growth factor CGF+Bio-Oss bone meal mixture(25 cases),with 25 teeth in each group.The changes of alveolar ridge bone height and width between the two groups were measured by CBCT immediately after surgery and 6 months after surgery.The effect of site preservation was further evaluated by postoperative pain,soft tissue wound healing rate,and new bone contour score.Results:Compared with the control group,the score of new bone contour and VAS scores of the experimental group were not statistically significant(P>0.05).In terms of soft tissue wound healing,the experimental group was superior to the control group,with a first grade healing rate of 52%in the experimental group and 16%in the control group.The experimental group's healing rate was greater than the control group,and the difference was statistically significant(P<0.05).Compared with the control group,the experimental group had an advantage in reducing alveolar bone height absorption(P<0.05).Conclusion:Using sticky bone can effectively reduce alveolar bone resorption to vertical height following tooth extraction,also has advantages in the soft tissue wound healing,strengthening the preservation of tooth extraction site,and is worthy of further promotion in clinical practice.