首页|Relationship between the temperature and the acoustic nonlinearity parameter in biological tissues
Relationship between the temperature and the acoustic nonlinearity parameter in biological tissues
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Recently with the rapid development of the high-intensity focused ultrasound (HIFU) in biomedical ultrasound, much attention has been paid to the noninvasive temperature estimation in biological tissue in order to determine the region and degree of the ultrasound-induced lesions. In ultrasound hyperthermal therapy it is highly desirable to study the real-time noninvasive monitoring of temperature distribution in biological tissue. In this paper, the relationship between the nonlinearity parameter B/A and the temperature in biological tissue is studied and compared with the theoretical model as well as the experimental results from the thermocouple. Results indicated that B/A could be used as an effective tool to monitor the temperature distribution in biological media.
acoustic nonlinearity parameternoninvasive temperature estimationultrasound therapyHIFUthermocouple
LU Ying、Liu Xiaozhou、Gong Xiufen、ZHANG Dong
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State Key Laboratory of Modern Acoustics, Institute of Acoustics, Nanjing University, Nanjing 210093, China