首页|Innovation for ascertaining genomic islands in PAO1 and PA14 of Pseudomonas aeruginosa
Innovation for ascertaining genomic islands in PAO1 and PA14 of Pseudomonas aeruginosa
扫码查看
点击上方二维码区域，可以放大扫码查看
原文链接
NETL
NSTL
万方数据
Based on three distinct traits of genomic islands,a novel approach was developed to search for and determine genomic islands in special strains.Two genomic islands in Pseudomonas aeruginosa PAO1 and 7 genomic islands in Pseudomonas aeruginosa PA14 were defined with this method.Among the 9 genomic islands,4 islands had been characterized before,while the other 5 islands were initially determined.The insert sites of 6 genomic islands are tRNA sequences,direct repeats of PA14GI-3 are relative to tRNA~(Lau),and direct repeats of PA14GI-2 are at the 3'end of bifunctional GMP synthase/giutamine amidotransferase.Only direct repeats of PA14GI-4 are not clear.Among the 5 newly-found genomic islands,it was supposed that PA14GI-2 is a genomic island related to Hg~(2+) uptake,PA14GI-3 is a secretory activity genomic island,PA14GI-6 is a pathogenicity island,and functions of PA14GI-1 and PA14GI-5 are not clear.Finally,the tyrosine type integrases in PAOIGI-1,PA14GI-5 and PA14GI-7 were analyzed,and their binding and restriction sites were predicted.
Pseudomonas aeruginosagenomic island (GI)horizontal gene transfer (HGT)comparative genome analysisintegrase
SONG Lei、ZHANG XueHong
展开 >
Key Laboratory of Microbial Metabolism,Ministry of Education,School of Life Sciences and Biotechnology,Shanghai Jiao Tong University,Shanghai 200240,China
College of Life and Environment Science,Shanghai Normal University,Shanghai 200234,China
NETL
NSTL
万方数据
