Department of Bioinformatics and Systems Biology,MOE Key Laboratory of Molecular Biophysics,Hubei Bioinformatics and Molecular Imaging Key Laboratory,College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan 430074,China

Key Laboratory of Birth Defects and Related Diseases of Women and Children,Department of Paediatrics,West China Second University Hospital,State Key Laboratory of Biotherapy,Sichuan University,Chengdu 610041,China

Department of Biochemistry & Research Center of Clinical Pharmacy of The First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou 310058,China

Institute of Biomedical Engineering,Chinese Academy of Medical Sciences and Peking Union Medical College,Tianjin 300192,China

Nanjing University Institute of Artificial Intelligence Biomedicine,Nanjing 210031,China