Objective To analyze the clinical effectiveness of ritodrine in the treatment of threatened preterm labor with premature rupture of membranes. Methods A total of 76 patients with premature rupture of membranes admitted to our hospital from May 2020 to December 2021 were selected and randomly divided into study group and control group, with 38 cases in each group. The study group was treated with ritodrine, while the control group was treated with magnesium sulfate. After the treatment, the clinical efficacy of the two groups was analyzed. Results The disappearance time of contractions in the study group was shorter than that in the control group, the prolongation time of pregnancy was longer, and the birth weight of newborns was greater than that in the control group, the difference was statistically significant (P＜0.05). In the study group, 5 cases (13.16％) extended the time more than 2 weeks, 7 cases (18.42％) extended the time more than 1 week, 19 cases (50.00％) extended the time more than 48 h, 31 cases successfully, the success rate is 81.58％; In the control group, there were 2 cases (5.26％) whose extended time was more than 2 weeks, 5 cases (13.16％) whose extended time was more than 1 week, 13 cases (34.21％) whose extended time was more than 48 h, and 20 cases were successfully protected, with a success rate of 52.63％. Compared with the study group, the fetal protection situation was more ideal and the success rate was higher, the difference was statistically significant (P＜0.05). The number of patients with tachycardia and chest tightness in the study group was 0, but there was one patient with headache and one patient with hypokalemia, and the incidence of adverse reactions in this group was 5.26％. In the control group, there were 2 patients with tachycardia and hypokalemia, 3 patients with chest tightness and 1 patient with headache, respectively. The incidence of adverse reactions in this group was 21.05％. The incidence of adverse reactions was lower in the study group, and the difference was statistically significant (P＜0.05). Conclusion The use of ritodrine in the treatment of patients with premature rupture of membranes can produce more ideal clinical therapeutic effect, and less adverse reactions, and has a positive impact on shortening the time of contraction of patients and the success rate of fetal protection.
Ritojunpremature rupture of membranes threatened preterm deliveryclinical effectiveness
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