首页|酒石酸布托啡诺复合丙泊酚用于无痛胃镜检查中的效果

酒石酸布托啡诺复合丙泊酚用于无痛胃镜检查中的效果

Effect of Butorphanol tartrate combined with propofol in painless gastroscopy

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目的 将丙泊酚与酒石酸布托啡诺用于无痛胃镜检查中,分析二者复合麻醉的效果.方法 将2018年6月~2021年8月在本院行无痛胃镜检查的98例患者纳入本研究中,采用双盲法随机分组,两组患者采用不同的麻醉用药方案.对照组患者实施丙泊酚+芬太尼麻醉,试验组实施丙泊酚+酒石酸布托啡诺麻醉.观察与对比两组患者麻醉苏醒时间、丙泊酚使用剂量、睫毛反射消失时间、入室后、置镜中、出镜后的平均动脉压、心率、血氧饱和度以及不良反应发生率.结果 试验组患者的麻醉苏醒时间、睫毛反射消失时间更短,丙泊酚使用剂量更少,与对照组比较,差异有统计学意义(P < 0.05).试验组患者置镜中以及出镜后平均动脉压、心率以及血氧饱和度指标均优于对照组,差异有统计学意义(P < 0.05).试验组呼吸抑制等不良反应发生率显著低于对照组,差异有统计学意义(P < 0.05).结论 在无痛胃镜检查中,采用酒石酸布托啡诺复合丙泊酚麻醉可以更快起效,患者检查后更易苏醒,能够减少丙泊酚的用量以及不良反应的发生,安全性更高.
Objective To analyze the effect of combined anesthesia of propofol and Butorphanol tartrate in painless gastroscopy. Methods A total of 98 patients who underwent painless gastroscopy in our hospital from June 2018 to August 2021 were included in this study. The patients in the two groups were randomized by double-blind method, and different anesthesia medication regimens were used in the two groups. Control group was anesthetized with propofol + fentanyl, experimental group was anesthetized with propofol + butorphanol tartrate. The anesthesia recovery time, the dosage of propofol, the disappearance time of eyelash reflex, the mean arterial pressure, heart rate, oxygen saturation and the incidence of adverse reactions were observed and compared between the two groups. Results The recovery time of anesthesia and disappearance time of eyelash reflex in experimental group were shorter, and the dosage of propofol was less. Compared with control group, the difference was statistically significant (P<0.05). The mean arterial pressure, heart rate and oxygen saturation indexes of experimental group were better than those of control group during and after implantation, with statistical significance (P<0.05). The incidence of respiratory depression and other adverse reactions in China experimental group was significantly lower than that in control group, the difference was statistically significant (P<0.05). Conclusion in painless gastroscopy, the use of butorphanol tartrate combined with propofol anesthesia can take effect more quickly, patients are more likely to recover after examination, and can reduce the dosage of propofol and the occurrence of adverse reactions, with higher safety.

painless gastroscopePropofolButorphanol tartratetime of recoveryvital signsadverse reaction

孙志君

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山东省烟台市蓬莱中医医院麻醉科,山东 烟台 265600

无痛胃镜 丙泊酚 酒石酸布托啡诺 苏醒时间 生命体征 不良反应

2023

科学养生
中国医院管理杂志社

科学养生

影响因子:0.019
ISSN:1672-9714
年,卷(期):2023.26(2)
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