科学养生2023，Vol.26Issue(2) ：72-74.DOI:10.3969/j.issn.1672-9714.2023.02.096

老年股骨粗隆下骨折加长型PFNA内固定术后早期应用伊班膦酸钠抗骨质疏松治疗的临床研究

Early application of lengthening PFNA internal fixation for senile subtrochanteric fracture of femur Clinical study of Ibandronate sodium in the treatment of osteoporosis

Li Jie-bing 田振峰 Bi Wei-dong 梁丙寅 Dong Zhi-hui
科学养生2023，Vol.26Issue(2) ：72-74.DOI:10.3969/j.issn.1672-9714.2023.02.096
✕
  • 万方数据

老年股骨粗隆下骨折加长型PFNA内固定术后早期应用伊班膦酸钠抗骨质疏松治疗的临床研究

Early application of lengthening PFNA internal fixation for senile subtrochanteric fracture of femur Clinical study of Ibandronate sodium in the treatment of osteoporosis

Li Jie-bing 1田振峰 2Bi Wei-dong 1梁丙寅 2Dong Zhi-hui1
扫码查看

作者信息

  • 1. Department of Orthopedics, Shijiazhuang People's Hospital, Shijiazhuang 050000, China
  • 2. 石家庄市人民医院骨科,河北 石家庄 050000
  • 折叠

摘要

目的 探讨术后早期应用伊班膦酸钠对于减少老年股骨粗隆下骨折行加长髓内钉(PFNA)内固定手术患者术后骨质疏松的疗效.方法 选取本院2017年1月～2018年7月行加长型PFNA内固定治疗的67例股骨粗隆下骨折患者,随机分为实验组(37例)和对照组(30例),分别于术后2周静点伊班膦酸钠2 mg(250 mL)和生理盐水(250 mL).两组患者均长期服用钙尔奇D 600 mg.比较两组患者的骨折愈合时间,3个月髋关节Harris评分,6个月、1年对侧髋关节的骨密度值变化,以及再骨折的发生率.结果 共有64例患者完成随访1年,实验组术后骨折愈合时间为(11.08±1.723)周,对照组骨折愈合时间为(12.08±1.513)周,差异有统计学意义(P ＞ 0.05).术后3月时,实验组患髋关节Harris评分为(85.15±3.71)分,对照组对侧髋关节Harris评分为(67.58±3.49)分,差异有统计学意义(P ＜ 0.05).术后6个月,实验组对侧髋关节骨密度为(-2.58±3.723)g/cm2,对照组对侧髋关节骨密度为(-5.58±3.423)g/cm2,差异有统计学意义(P ＜ 0.05).术后1年,实验组对侧髋关节骨密度为(1.58±3.32)g/cm2,对照组对侧髋关节骨密度为(-5.38±2.423)g/cm2,差异有统计学意义(P＜ 0.05).对照组出现1例术后1年骨折不愈合.结论 老年股骨粗隆下骨折行加长型PFNA内固定术后早期应用伊班膦酸钠可起到治疗骨质疏松的作用,同时能在一定程度上缩短骨折愈合时间.

Abstract

Objective To investigate the effect of early postoperative application of Ibandronate sodium on reducing postoperative osteoporosis in elderly patients with subtrochanteric fracture of femur who received lengthening intramedullary nail (PFNA) internal fixation. Methods 67 patients with subtrochanteric fracture of femur who received extended PFNA internal fixation from January 2017 to July 2018 were selected and randomly divided into experimental group (37 cases) and control group (30 cases). The patients were given 2 mg of ibandronate sodium (250 mL) and normal saline (250 mL) 2 weeks after surgery, respectively. Patients in both groups were given calcitci D 600 mg for a long time. Fracture healing time, 3-month Harris hip score, 6-month and 1-year changes in bone density values of the contralateral hip, and incidence of refracture were compared between the two groups. Results A total of 64 patients completed 1 year follow-up, the fracture healing time of the experimental group was (11.08±1.723) weeks, the fracture healing time of the control group was (12.08±1.513) weeks, the difference was statistically significant (P＞0.05). Three months after surgery, the Harris score of hip joint in the experimental group was (85.15±3.71) points, and the Harris score of contralateral hip joint in the control group was (67.58±3.49) points, the difference was statistically significant (P＜0.05). Six months after surgery, the bone mineral density of the contralateral hip joint of the experimental group was (-2.58±3.723) g/cm2, and that of the control group was (-5.58±3.423) g/cm2, the difference was statistically significant (P＜0.05). One year after surgery, the bone density of the contralateral hip joint in the experimental group was (1.58±3.323) g/cm2, and that in the control group was (-5.38±2.423) g/cm2, the difference was statistically significant (P＜0.05). Fracture nonunion occurred in 1 case in control group 1 year after operation. Conclusion Early application of ibandronate sodium after extended PFNA internal fixation for senile femoral subtrochanteric fractures can treat osteoporosis and shorten fracture healing time to a certain extent.

关键词

股骨粗隆下骨折/伊班膦酸钠/股骨近端髓内钉/骨质疏松/骨密度

Key words

subtrochanteric fracture of femur/ibandronate sodium/proximal femoral intramedullary nail/osteoporosis/bone density

引用本文复制引用

出版年

2023
科学养生
中国医院管理杂志社

科学养生

影响因子：0.019
ISSN：1672-9714
参考文献量11
段落导航相关论文