Difference analysis of postoperative cognitive dysfunction in elderly patients with different depths of anesthesia
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目的 分析不同麻醉深度下老年患者术后认知功能障碍发生的差异.方法 对2019年7月～2020年7月在本院行腹腔镜手术的92例老年患者进行研究,采用信封法随机分组,各46例.对照组术中麻醉深度维持在50～59,研究组术中麻醉深度维持在40～49.比较两组患者术后12 h、24 h以及48 h MMSE评分、苏醒时间、拔管时间、定向力恢复时间.结果 两组患者术后12 h MMSE评分与术前相比均有所下降,研究组术后12 h、24 h以及48 h MMSE评分均高于对照组,差异具有统计学意义(P＜ 0.05).研究组患者苏醒时间、拔管时间与定向力恢复时间短于对照组,差异具有统计学意义(P ＜ 0.05).研究组患者术后认知功能障碍发生率明显低于对照组,差异具有统计学意义(P ＜ 0.05).结论 老年腹腔镜手术中BIS值维持在40～49范围内可以减少术后认知功能障碍的发生率,对患者的认知功能影响小,患者苏醒、定向力恢复更快.
Objective To analyze the difference of postoperative cognitive dysfunction in elderly patients with different depth of anesthesia. Methods A total of 92 elderly patients who underwent laparoscopic surgery in our hospital from July 2019 to July 2020 were studied. They were randomly assigned by envelope method, with 46 patients in each group. The anesthesia depth of the control group was maintained at 50 ～ 59, while that of the study group was maintained at 40 ～ 49. The score of 12 h, 24 h and 48 h MMSE, recovery time, extubation time and recovery time of directional force were compared between the two groups. Results The postoperative 12 h MMSE scores of both groups were decreased compared with those before surgery, and the postoperative 12 h, 24 h and 48 h MMSE scores of the study group were higher than those of the control group, the difference was statistically significant (P＜0.05). The recovery time, extubation time and orientation recovery time of the study group were shorter than those of the control group, and the difference was statistically significant (P＜0.05). The incidence of postoperative cognitive dysfunction in the study group was significantly lower than that in the control group, and the difference was statistically significant (P＜0.05). Conclusion The BIS value in the range of 40 ～ 49 can reduce the incidence of postoperative cognitive dysfunction in the elderly patients with laparoscopic surgery, little impact on the cognitive function of the patients, faster recovery of recovery, orientation.
cognitive dysfunctiondepth of anesthesialaparoscopic surgeryMMSE score
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