首页|艾普拉唑治疗胃食管反流病对患者胃功能的影响

艾普拉唑治疗胃食管反流病对患者胃功能的影响

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目的 探讨胃食管反流病患者采用艾普拉唑治疗的临床效果以及对胃功能的影响。方法 抽取本院2021年2月~2022年6月接受治疗的胃食管反流病患者100例为研究对象,按照随机盲选法平分为对照组和观察组,各50例。对照组实施奥美拉唑肠溶胶囊联合枸橼酸莫沙必利分散片治疗,观察组在对照组治疗方案基础上应用艾普拉唑治疗,比较观察组和对照组患者治疗效果、胃肠道功能及不良反应发生情况。结果 ①摄入食物时间、排气时间、肠鸣音恢复时间、排便时间、住院时间、胃肠功能恢复时间观察组均短于对照组,差异有统计学意义(P < 0。05)。②观察组治疗总有效率高于对照组,差异有统计学意义(P < 0。05)。③观察组头晕、胃肠道不适等不良反应发生率较对照组低,差异有统计学意义(P < 0。05)。结论 针对胃食管反流病患者实施艾普拉唑治疗的临床效果突出,可改善胃肠功能,加快患者病情康复,且安全性高。
Effect of eprazole on gastric function in patients with gastroesophageal reflux disease
Objective To investigate the clinical effect of eprazole on gastric function in patients with gastroesophageal reflux. Methods 100 patients with gastroesophageal reflux disease who received treatment in our hospital from February 2021 to June 2022 were selected as research objects, and divided into control group and observation group with 50 patients in each group according to random blind selection method. The control group was treated with omeprazole enteric-coated capsules combined with Mosapride citrate dispersive tablets. The observation group was treated with eprazole on the basis of the treatment scheme of the control group. The therapeutic effect, gastrointestinal function and occurrence of adverse reactions were compared between the observation group and the control group. Results ① Food intake time, exhaust time, bowel sound recovery time, defecation time, hospital stay time, gastrointestinal function recovery time of observation group were shorter than control group, the difference was statistically significant (P<0.05). ② The total effective rate of the observation group was higher than that of the control group, and the difference was statistically significant (P<0.05). ③ The incidence of dizziness, gastrointestinal discomfort and other adverse reactions in the observation group was lower than that in the control group, and the difference was statistically significant (P<0.05). Conclusion The clinical effect of eprazole on patients with gastroesophageal reflux disease is outstanding, which can improve gastrointestinal function and accelerate the recovery of patients with high safety.

Eprazolegastroesophageal reflux diseasegastric functioncurative effectsecurity

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安徽省枞阳县人民医院消化内科,安徽 铜陵 246700

艾普拉唑 胃食管反流病 胃功能 疗效 安全性

2023

科学养生
中国医院管理杂志社

科学养生

影响因子:0.019
ISSN:1672-9714
年,卷(期):2023.26(4)
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