科学养生2023,Vol.26Issue(4) :79-81.DOI:10.3969/j.issn.1672-9714.2023.04.093

联合检测血浆纤维蛋白原、D-二聚体在老年髋部骨折患者中的意义

Combined determination of fibrinogen and D-dimer in elderly patients with hip fracture

石芸 Liu Shi-chang
科学养生2023,Vol.26Issue(4) :79-81.DOI:10.3969/j.issn.1672-9714.2023.04.093

联合检测血浆纤维蛋白原、D-二聚体在老年髋部骨折患者中的意义

Combined determination of fibrinogen and D-dimer in elderly patients with hip fracture

石芸 1Liu Shi-chang2
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作者信息

  • 1. 赣州市南康区第一人民医院检验科,江西 赣州 341400
  • 2. Department of Clinical Laboratory, The First People's Hospital of Ganzhou Nankang District, Ganzhou 341400, China
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摘要

目的 探讨联合检测血浆纤维蛋白原(Fibrinogen,Fg)和D-二聚体(D-dimer,DD)在老年髋部骨折患者中的意义.方法 选择本院2020年7月~2022年7月收治的老年髋部骨折患者155例,根据术后是否出现DVT分为两组,即骨折术后未出现DVT组、骨折术后出现DVT组,并检测其术前及术后24 h血浆纤维蛋白原(Fg)和D-二聚体(DD),并与健康体检职工正常对照组进行对比分析.结果 骨折术后未出现DVT组及骨折术后出现DVT组术前血浆Fg、DD值均高于健康对照组,差异有统计学意义(P < 0.05).骨折术后出现DVT组术后24 h与术前相比较,血浆Fg、DD明显偏高,差异有统计学意义(P < 0.05);骨折术后未出现DVT组血浆Fg、DD值低于骨折术后出现DVT组,差异有统计学意义(P < 0.05);骨折术后未出现DVT组血浆Fg、DD值术前术后相比较,血浆Fg、DD稍偏高,差异无统计学意义(P > 0.05).结论 联合检测血浆Fg、DD对预测、评估深静脉栓塞的发生、发展有着重要的早期诊断参考价值.

Abstract

Objective To explore the significance of combined detection of plasma Fibrinogen (Fg) and D-dimer (DD) in elderly patients with hip fracture. Methods 155 elderly patients with hip fracture in our hospital were selected and divided into two groups according to the occurrence of DVT after fracture, that is, the group without DVT after fracture and the group with DVT after fracture. Plasma fibrinogen (Fg) and D-dimer (DD) were detected before and 24 h after fracture, and compared with the healthy control group. Results The group without DVT after fracture surgery and the group with DVT after fracture surgery, the preoperative plasma Fg and DD values were higher than those of healthy control group, the difference was statistically significant (P<0.05). Compared with the preoperative group 24 h after fracture, plasma Fg and DD in DVT group were significantly higher, the difference was statistically significant (P<0.05). The plasma Fg and DD values in the group without DVT after fracture surgery were lower than those in the group with DVT after fracture surgery, and the difference was statistically significant (P<0.05). The plasma Fg and DD values of DVT group were slightly higher than those of DVT group before and after fracture surgery, with no statistical significance (P>0.05). Conclusion The combined detection of plasma Fg and DD has important early diagnostic value for predicting and evaluating the occurrence and development of deep vein embolism.

关键词

老年髋部骨折/深静脉血栓/纤维蛋白原/D-二聚体

Key words

senile hip fracture/deep vein thrombosis/fibrinogen/D-dimer

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出版年

2023
科学养生
中国医院管理杂志社

科学养生

影响因子:0.019
ISSN:1672-9714
参考文献量11
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