首页|D-二聚体和降钙素原检测在脓毒症中的应用

D-二聚体和降钙素原检测在脓毒症中的应用

Application of D-dimer and procalcitonin detection in sepsis

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目的 探讨血清D-二聚体和降钙素原水平检测在脓毒症中的应用价值.方法 选取2019年5月~2022年5月本院收治的78例脓毒症患者为观察组,并且在相同的时间段内收集到本院进行健康体检的受检78例,将其作为对照组.检测两组的血清D-二聚体和降钙素原水平,且检测观察组治疗前后的血清D-二聚体和降钙素原水平.将观察组分为脓毒症休克10例(观察组A)、重度脓毒症15例(观察组B)和脓毒症53例(观察组C),比较以上三组血清D-二聚体和降钙素原水平的差距.结果检测血清D-二聚体和降钙素原情况得出的结果是,观察组的数值更高,和对照组比较差异有统计学意义(P < 0.05);经过治疗后,观察组的两个指标(血清D-二聚体、降钙素原)均呈现出较大的变化,和治疗前比较差异有统计学意义(P < 0.05);而将观察组分为三组后检测,结果显示两个指标观察组C的数据最低,其次是观察组B,最高是观察组A,组间差异有统计学意义(P< 0.05).结论 血清D-二聚体和降钙素原水平检测在脓毒症中具有比较高的应用价值.
Objective To investigate the application value of detection of serum D-dimer and procalcitonin levels in sepsis. Methods 78 patients with sepsis admitted to our hospital from May 2019 to May 2022 were selected as the observation group, and 78 patients who underwent physical examination in our hospital during the same period of time were collected as the control group. Serum D-dimer and procalcitonin levels of the two groups were detected, and serum D-dimer and procalcitonin levels of the observation group before and after treatment were detected. The observation group was divided into 10 cases of septic shock (observation group A), 15 cases of severe sepsis (observation group B) and 53 cases of sepsis (observation group C). The differences of serum D-dimer and procalcitonin levels among the three groups were compared. Results The serum D-dimer and procalcitonin were detected in the observation group, and the difference was statistically significant compared with the control group (P<0.05). After treatment, two indexes (serum D-dimer and procalcitonin) in the observation group showed significant changes, and the difference was statistically significant compared with before treatment (P<0.05). The observation group was divided into three groups, and the results showed that the data of observation group C was the lowest, followed by observation group B, and the highest was observation group A, and the difference between groups was statistically significant (P<0.05). Conclusion The detection of serum D-dimer and procalcitonin levels is of high application value in sepsis.

D-dimerprocalcitonindetection valuesepsis

马春娟

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陕西省宝鸡市眉县人民医院,陕西 宝鸡 722300

D-二聚体 降钙素原 检测价值 脓毒症

2023

科学养生
中国医院管理杂志社

科学养生

影响因子:0.019
ISSN:1672-9714
年,卷(期):2023.26(4)
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