Strategic change and organizational resilience are crucial in adapting to environmental changes and resisting external shocks for firms,but little research digs out the relationship between them.Based on the empirical data of A-share listed com-panies in Shanghai and Shenzhen from 2007 to 2020,this paper used a panel regression model to explore the impact of corporate strategic change on organizational resilience,and analyzed the external business environment and internal operating conditions'effects on their relation.The results showed that the strategic changes significantly reduce organizational resilience,and they are manifested as an increase in the degree of loss and an extension of recovery time when the firm is exposed to external shocks.As the uncertainty of the business environment increases,the negative impact of strategic changes on organizational resilience will be exacerbated.Whereas,when business performance is good,strategic changes will not hurt organizational resilience.Only when business performance is poor will strategic changes exacerbate the degree of loss and extend the recovery time.This paper not on-ly expanded the research literature on the consequences of strategic change and the antecedents of organizational resilience but al-so will provide a reference for firms to implement strategic change.