Objective To explore the independent risk factors of severe refractory Mycoplasma pneumoniae pneumonia(SRMPP)complicated with bronchitis obliterans in children.Methods The clinical data of children with SRMPP admitted to the Department of Pediatrics from October 2021 to October 2023 were retrospectively analyzed.All patients were divided into two groups:one group had the sequelae of bronchitis obliterans(occluded group)and the other group had not bronchitis obliterans(non-occluded group),and the differences in clinical characteristics between the two groups were compared.Multivariate logistic regression was used to analyze the independent risk factors of SRMPP complicated with bronchiolitis obliterans,and receiver operating characteristic(ROC)curve was used to analyze the predictive value of each factor for SRMPP complicated with bronchiolitis obliterans.Results A total of 110 SRMPP children(60 boys and 50 girls)with a median age of 6.0(4.0-8.0)years were included,40 of whom were complicated with obliterated bronchitis.Multivariate logistic regression analysis showed that increased D-dimer level and plastic mucus plugs were independent risk factors for SRMPP complicated with bronchiolitis obliterans(P<0.05),while high levels of prealbumin were independent protective factor(P<0.05).ROC curve analysis showed that the areas under the ROC curve(AUC)of D-dimer increase,prealbumin decrease and plastic mucus plugs in predicting SRMPP complicated with bronchitis obliterans were 0.69,0.74 and 0.70,respectively.Conclusions For SRMPP children with serum prealbumin level≤13.2 mg/dL,plasma D-dimer level≥1.85 mg/L,and plastic mucus plug formation,it is necessary to be alert to the occurrence of bronchitis obliterans.
关键词
重症难治性肺炎支原体肺炎/闭塞性支气管炎/儿童
Key words
severe refractory Mycoplasma pneumoniae pneumonia/bronchitis obliteran/child
维普
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