首页|重连口服液联合抗感染治疗成人社区获得性肺炎临床研究

重连口服液联合抗感染治疗成人社区获得性肺炎临床研究

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目的 对重连口服液联合抗感染用于成人社区获得性肺炎(community acquired pneumonia,CAP)患者的临床治疗效果以及临床不良反应予以观察。方法 成人CAP患者80例,通过随机分组,形成对照组和治疗组,每组各40例。对照组采用传统的西医学临床治疗方案,治疗组在此治疗基础上使用重连口服液。对治疗组和对照组患者的临床症状改善程度以及药物应用效果进行观察,比较两组治疗前后的血常规、炎性相关指标以及临床不良反应。结果 治疗组比对照组有更高的治疗总有效率(P<0。05);治疗组比对照组患者的肺部湿啰音及咳嗽等主要症状消失时间明显缩短(P均<0。01);两组经药物治疗后相关炎症指标如:高敏C-反应蛋白(hs-CRP)、外周血降钙素原(PCT)、血清淀粉样蛋白A(SAA)、中性粒细胞百分比(Neu%)、白介素-6((IL-6)、白细胞计数(WBC)水平均显著下降(P均<0。05),但治疗组治疗后较对照组治疗后下降更为明显(P均<0。05);两组患者治疗期间均无不良反应。结论 重连口服液与抗感染联合治疗成人CAP患者具有显著的临床治疗成效,能对患者肺部感染进行有效把控,同时也能够缓解患者畏寒发热、咳嗽、咳痰等不适状况,且没有明显不良反应出现,能够在临床中进行推广应用。
Clinical study on Chonglian Oral Liquid combined with anti-infection in the treatment of adult community-acquired pneumonia
Objective To observe the clinical therapeutic effect and clinical adverse reactions of Chonglian Oral Liquid combined with anti-infection in patients with adult community acquired pneumonia(CAP).Methods 80 adult patients with CAP were randomly divided into a control group and a treatment group,with 40 cases in each group.The control group was treated with traditional Western medicine,and the treatment group was treated with Zhuanglian oral liquid.The improvement degree of clinical symptoms and the effect of drug application in the treat-ment group and the control group were observed,and the blood routine,inflammation-related indexes,and clinical adverse reactions before and after treatment were compared between the two groups.Results The total effective rate of the treatment group was higher than that of the control group(P<0.05).The disappearance time of main symp-toms such as lung rales and cough in the treatment group was significantly shorter than that in the control group(P<0.01).Relevant inflammatory indicators after drug treatment in both groups are as follows:The levels of high-sensi-tivity C-reactive protein(hs-CRP),peripheral blood procalcitonin(PCT),serum amyloid A(SAA),neutrophil percentage(Neu%),interleukin-6(IL-6)and white blood cell count(WBC)were significantly decreased(P<0.05).However,the decrease was more obvious in the treatment group than in the control group(all P<0.05).There were no adverse reactions during treatment in both groups.Conclusion The combination of Chonglian Oral Liquid and anti-infection has a significant clinical effect in the treatment of adult CAP patients.It can effectively con-trol the pulmonary infection of patients,and can also alleviate the discomfort of patients such as chills,fever,cough,and expectoration,and there are no obvious adverse reactions.It can be popularized and applied in clinical practice.

CAPChonglian Oral Liquidcurative effectinflammatory index

方莉、杨程、童佳兵、高雅婷、童祥丽

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230032 安徽合肥,安徽中医药大学第一附属医院

230031 安徽合肥,安徽中医药大学

社区获得性肺炎 重连口服液 疗效 炎症指标

2025

临床肺科杂志
安徽医科大学 解放军第105医院

临床肺科杂志

影响因子:1.42
ISSN:1009-6663
年,卷(期):2025.30(1)