An epidemiological study of six common respiratory pathogens in children in Nanjing from 2023 to 2024
Objective To study the epidemiology and characteristics of children with respiratory tract infec-tious diseases from May 2023 to April 2024 in Nanjing and its surrounding areas,and to determine the types of patho-gens,to provide evidence for the prevention and treatment of respiratory tract infectious diseases.Methods The samples of 88437 children from Nanjing Children's Hospital from May 2023 to April 2024 were retrospectively ana-lyzed.Six pathogens,namely adenovirus(ADV),influenza A virus(FluA),influenza B virus(FluB),and human rhinovirus(HRV),were detected by fluorescent PCR.Mycoplasma pneumonia(MP)and respiratory syncytial virus(RSV)were analyzed statistically.Results The positive detection rate of 88437 samples was 68.98％,and the de-tection rates of six pathogens were respectively MP25.77％,ADV15.24％,HRV12.18％,RSV11.51％,FluA8.25％,and FluB7.24％from high to low.There were significant differences in the detection rate of each pathogen among different age groups,and the highest detection rate was found in children aged 7-18 years.The pos-itive rate was also higher in autumn and winter due to time factors.Among them,the detection rates of MP,Flu A,and Flu B have alternating peaks and the state of decline and decline.The positive rate of mixed infection in different pathogens was also high,among which the most common was a mixed infection of HRV and MP.Conclusion MP infection is the most common respiratory tract pathogen infection in children,among which MP,Flu A and Flu B have alternating peaks,HRV and MP are the most common mixed infection,and different ages and times have effects on pathogen infection.Pathogen infection is more common in children aged 7-18 years,and the education of respiratory tract infection knowledge for children aged 7-18 years should be strengthened.Autumn and winter are the high-incidence seasons of respiratory infection,so it is necessary to strengthen the protection and monitoring in au-tumn and winter.
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