磁共振T2*评价长期输血患者肝脏铁过载的价值
The Evaluation of MR T2 * on Long Term Blood Transfusion in Patients with Liver Iron Overload
宋晓丽 1赵俊功 1吴正阳 1魏小二 1魏黎明1
作者信息
- 1. 200233上海,上海交通大学附属第六人民医院放射科
- 折叠
摘要
目的 探讨磁共振T2*在评估长期输血患者肝脏铁过载的价值.方法 搜集2011年12月至2012年6月长期输血患者28例,输血史12～ 69个月不等.应用Siemens Magnetom Trio 3.0 T磁共振设备的梯度回波序列对全部患者肝脏进行扫描并应用CMR tool软件(2010版)计算出肝脏感兴趣区域的T2*值；同时抽取患者静脉血,用紫外分光光度法检测血清铁蛋白水平.结果 28例患者的T2*值范围为0.9～17.8 ms,均数±标准差为(3.63±4.84) ms;血清铁蛋白浓度范围为118～7855 ng/ml,均数±标准差为(2098.60±1578.68) ng/ml.应用SPSS 16.0统计软件对T2*与血清铁蛋白进行相关性分析,两者呈负相关(P =0.015),相关系数为-0.535.结论 磁共振T2*在评估长期输血患者肝脏铁过载方面有一定价值.
Abstract
Objective To investigate the value of MR T2 * in evaluation of long term blood transfusion in patients with liver iron overload.Methods From December,2011 to June,2012,28 long term blood transfusion patients with history of blood transfusion ranging from 12-69 months were collected.Gradient echo sequence was applied for all patients with liver scan and the appropriate software was used to calculate the T2 * values of liver region of interest.At the same time,patients with venous blood taken,the serum ferritin level was detected by ultraviolet spectrophotometry..Results 28 patients with T2 * value ranged from 0.9-17.8 ms,mean ± standard deviation was (3.61 ± 4.84) ms; serum ferritin concentration ranged from 118-7855 ng/ml,mean ± standard deviation was the (2229.60 ± 1626.06) ng/ml.T2 * and serum ferritin was related using SPSS16.0 statistical software (P =0.015),correlation coefficient was-0.518.Conclusion MR T2 * has some value in assessing long term blood transfusion in patients with liver iron overload.
关键词
肝脏铁过载/磁共振/弛豫时间/血清铁蛋白Key words
Liver iron overload/Magnetic resonance imaging/Relaxation time/Serum ferritin引用本文复制引用
出版年
2013
NETL
NSTL
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