Objective Quantification of graft remodeling status at 6 and 12 months after anterior cruciate ligament re-construction(ACLR)using T2 mapping functional magnetic resonance and correlation with clinical scores.Methods Pa-tients who underwent ACLR between August 2020 and October 2021(n=40)were collected prospectively,and after ACL reconstruction patients underwent 3.0T conventional MRI and T2 mapping scans at 6 and 12 months after surgery to meas-ure the T2 values of the intra-articular segment of the graft and its three segments(proximal,middle and distal)after sur-gery.Independent samples t-tests were used to analyze the differences between the three segments and the intra-articular segment T2 values at 6 and 12 months post-operatively.Two-by-two comparisons were made using the LSD-t method for the three segments of the intra-articular segment.The International Knee Documentation Committee knee score(IKDC)was used for clinical function scores at 6 and 12 months postoperatively.Results The T2 values of the overall intra-articular segment of the ACL graft and its three segments(proximal,middle and distal)decreased significantly from 6 to 12 months(P＜0.001).The proximal segment of the intra-articular segment had higher T2 values than the middle and distal segments at 6 months postoperatively(P=0.026 and P=0.001),and the proximal segment of the intra-articular segment had higher T2 values than the distal segment at 12 months postoperatively(P＜0.001).There was a moderate negative correlation be-tween graft T2 values and IKDC scores at 6 months postoperatively(r=-0.508,P=0.001)and at 12 months postopera-tively(r=-0.559,P＜0.001).Conclusion T2 mapping can detect changes in graft intra-articular segment maturity from 6 months to 12 months after ACLR and has potential clinical application.
NETL
NSTL
维普
万方数据
