Objective To evaluate the effectiveness of percutaneous transhepatic biliary clamp biopsy in the diagnosis of biliary stent re-obstruction.Methods From December 2015 to December 2019,31 patients with stent re-obstruction af-ter biliary stent implantation[19 males and 12 females,aged 47-83 years,mean age(61.5±11.3)years]underwent percutaneous transhepatic biliary clamp biopsy under fluoroscopy guidance.The technical success rate,complications,oper-ation time and average number of biopsies were evaluated,and the sensitivity,specificity,accuracy,positive predictive rate and negative predictive rate were analyzed.Results The technical success rate was 100%,the average operation time was(23.0±6.3)min,the average number of biopsies was 3.9±0.6,and the incidence of complications was 9.7%,including 2 cases of biliary bleeding and 1 case of cholangitis.There were no serious complications such as massive hemorrhage and bile duct perforation.Twenty-three cases were correctly diagnosed as malignant tumors,three were diagnosed as true-nega-tive,five were diagnosed as false-negative,and there were no false-positive diagnoses.The diagnostic performance of biliary clamp biopsy for stent re-obstruction:the sensitivity was 79.3%(23/29),the specificity was 100%(3/3),the accuracy was 83.9%(26/31),the positive predictive rate was 100%(23/23),and the negative predictive rate was 37.5%(3/8).Conclusion Percutaneous transhepatic biliary clamp biopsy under fluoroscopy is safe and feasible in the diagnosis of bili-ary stent re-obstruction.
Bile duct obstructionBile duct stentObstructionClamp biopsy