Objective To compare CT quantitative parameters and clinical pulmonary function in patients with type 2 diabetic pulmonary injury,analyze the imaging changes of type 2 diabetic pulmonary injury,and explore image-sensitive in-dicators of T2DM pulmonary injury.Methods According to the results of pulmonary function test,the imaging data of 96 patients with type 2 diabetes mellitus(T2DM)with pulmonary function damage were retrospectively collected,and the quantitative parameters of CT were obtained by"digital lung"processing,mainly including double lung volume,the volume(LAA910,LAA950)of the density attenuation area below-910 HU and-950 HU in both lungs as a percentage of the whole lung(LAA910% ,LAA950% ),the average density,and another 83 T2DM patients with normal lung function were included in the control group.The independent samples t test or Mann-Whitney U test were used to analyze the differences of the quantitative parameters of the lungs between the two groups.Results Compared with the normal control group,the pulmonary function parameters FVC,FVC% ,FEV1,FEV1% and the pulmonary CT quantitative indicators of total lung vol-ume,LAA910,LAA950,LAA910% ,and LAA950% in the lung damage group were significantly decreased(P<0.05).The mean density was significantly higher(P<0.05).Whole lung volume is most helpful in distinguishing T2DM lung damage and is a protective factor for T2DM lung damage.Conclusion The quantitative parameters of pulmonary CT can quantitatively reflect the lung damage in patients with T2DM,and those with larger whole lung volume can effectively avoid the reduction of pulmonary function in T2DM.
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