首页|MiT家族易位性肾癌影像诊断与鉴别诊断

MiT家族易位性肾癌影像诊断与鉴别诊断

Imaging Diagnosis and Differential Diagnosis of MiT Family Translocation Renal Cell Carcinoma

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目的 探讨MiT家族易位性肾细胞癌(MiT RCC)的影像表现及与肾透明细胞癌(CCRCC)及乳头状肾细胞癌(PRCC)的鉴别诊断价值.方法 选择经手术病理证实的 11 例MiT RCC患者CT及MRI影像资料,分析患者的性别及年龄、病灶大小、形态、出血、假包膜、强化模式、生长方式以及对周围组织侵犯等影像学特征,并与 11例CCRCC、11 例PRCC的影像特点对照分析.结果 11 例MiT RCC患者中男3 例,女8 例,年龄10~73 岁,平均(33.18±17.41)岁.11 例MiT RCC与11 例CCRCC和11 例PRCC 3 组间分析结果显示:患者年龄、性别、肿块位置、有无假包膜、有无出血、发病年龄分布、强化程度组间差异具有统计学意义(P<0.05);肿块大小及形态、钙化、坏死囊变、强化模式、生长方式、对组织侵犯以及转移征象差异无统计学意义(P>0.05).MiT RCC相比CCRCC、PRCC发病年龄更小,女性更多见,出血发生率更高,更易表现为肾髓内生长,假包膜MiT RCC及CCRCC发生率均较高,明显高于PRCC(P<0.05);强化程度CCRCC>MiT RCC>PRCC(P<0.01).结论 MiT RCC的影像学表现有一定特征性,结合好发于30 岁以下的儿童及年轻人、出现肾轮廓内肿块伴出血、钙化、假包膜、多发淋巴结及远处转移,有助于提高术前诊断率.
Objective To investigate the imaging features of MiT family translocation renal cell carcinoma(MiT RCC)and its differential diagnostic value with renal clear cell carcinoma(CCRCC)and papillary renal cell carcinoma(PRCC).Methods CT and MRI images of 11 patients with MiT RCC confirmed by surgery and pathology were selected.The ima-ging characteristics of the patients,such as gender,age,size,morphology,hemorrhage,pseudocapsule,enhancement pat-tern,growth pattern and invasion of surrounding tissues were analyzed,and the imaging characteristics were compared with those of 11 CCRCC and 11 PRCC.Results Among the 11 patients with MiT RCC,there were 3 males and 8 females.The average age of the patients was(33.18±17.41)years.The results of analysis among 11 MiT RCC,11 CCRCC,and 11 PRCC showed that there were statistically significant differences among the three groups in age,sex,tumor location,presence or absence of false capsule,presence or absence of hemorrhage,the age distribution of onset,and degree of en-hancement(P<0.05).There was no significant difference in the size and shape,calcification,necrotic cystic change,enhancement mode,growth mode,invasion to tissues and metastasis signs of the tumor(P>0.05).Compared with CCRCC and PRCC,MiT RCC has a younger age of onset,is more common in women,has a higher incidence of bleeding,and is more likely to show intrarenal growth.The incidence of pseudocapsule was higher in MiT RCC and CCRCC than that of PRCC(P<0.05).The enhancement degree was CCRCC>MiT RCC>PRCC(P<0.01).Conclusion The ima-ging manifestations of MIT RCC have certain characteristics.It is helpful to improve the preoperative diagnosis rate in com-bination with children and young people under the age of 30 years,and the presence of masses in the renal contour with hemorrhage,calcification,false capsule,multiple lymph nodes and distant metastasis.

MiT family translocation renal cell carcinomaClear cell renal cell carcinomaPapillary renal cell carci-nomaComputed tomographyMagnetic resonance imaging

赵娜、史彬、陈东、宋德梅、曹锋、高飞、董江宁

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230031 合肥,中国科学技术大学附属第一医院西区 安徽省肿瘤医院影像科

MiT家族易位肾细胞癌 肾透明细胞癌 乳头状肾细胞癌 计算机体层摄影术 磁共振成像

2024

临床放射学杂志
黄石市医学科技情报所

临床放射学杂志

CSTPCD北大核心
影响因子:0.872
ISSN:1001-9324
年,卷(期):2024.43(3)
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