首页|基于机器学习标准化积分面积算法的脊柱侧弯度量方法

基于机器学习标准化积分面积算法的脊柱侧弯度量方法

Measurement Method of Scoliosis Based on Standardized Integral Area Algorithm of Machine Learning

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目的 基于机器学习算法搜索全脊柱X线影像的行最大像素和像素局部极值,开发一种自动度量脊柱侧弯程度的计算机视觉评估方法.方法 搜集129 例特发性脊柱侧弯患者全脊柱正位X线影像,行直方图均衡后使用对称叠加阈值算法凸显出非对称像素,搜寻每行中最大亮度的像素点作为全局最大像素点,搜寻每行像素中比两侧3~5 个像素点高的局部极值点,以两种点的交集作为候选锚点.从最上面的候选锚点开始向第二行的候选锚点连直线,如连线斜率绝对值>1 则第二行的点即作为精细锚点.所有精细锚点用3 次样条算法进行拟合得到脊柱的近似曲线,以曲线与脊柱首尾相连的直线之间的标准化积分面积对脊柱侧弯程度进行度量.以人工测量Cobb角值为标准,评价人工测量Cobb角与积分面积算法度量的相关性,使用受试者工作特征曲线分析积分面积算法度量的曲线下面积.结果 人工测量Cobb角与积分面积算法度量呈正相关(r =0.658,P<0.001),积分面积算法度量中度、重度侧弯的受试者工作特征曲线下面积分别为 0.889、0.862.结论 本方法快速、高效地从全局角度评估脊柱侧弯的程度,适合于大面积脊柱侧弯程度评估的筛查,可作为脊柱侧弯角度精细测量的有益补充.
Objective To develop a computer vision evaluation method to automatically measure the degree of scoliosis based on the machine learning algorithm.Methods For 129 X-ray images of the coronal plane of spine from patients with idiopathic scoliosis,after histogram equalization of original image,we use flipping method to magnify asymmetric elements,search for the global maximum pixel value in each line,and then,scan local maximum pixel value with neighborhood 3-5.The intersection set of the two point sets can be regarded as candidate anchor points.In following filtering step,we begin with the highest point,connecting second line's candidate anchor points.If the slope absolute value of the line larger or e-qual to 1,then the second line's candidate anchor can be entitled as a fine anchor.All fine anchors were fitted with cubic spline algorithm to obtain the approximate curve of the spine,and the degree of scoliosis was measured by the standardized integral area.The correlation between the measured Cobb angle and the integrated area algorithm was evaluated.The area under the curve measured by the integrated area algorithm was analyzed by receiver operating characteristic curve(ROC).Results The Cobb angle measured by manual was positively correlated with the integrated area algorithm(r =0.658,P<0.001),and the AUC of the integrated area algorithm for moderate and severe lateral bending was0.889 and0.862.Con-clusion The integrated area algorithm method can quickly and efficiently assess the degree of scoliosis from a global per-spective.It is suitable for screening the degree of large area scoliosis assessment,and can be a useful supplement to the fine measurement of scoliosis angle.

Measuring scoliosisX-ray imageMachine learningExhaustive search algorithmsanchor pointsAn-chor pointNormalized area

张屹、韩殊曼、杨晨、韩晓楠、吴慧钊、曹磊、于宝海、吴文娟

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050051 石家庄,河北科技大学

河北医科大学第三医院放射科

脊柱侧弯度量 X线影像 机器学习 穷尽搜索算法 锚点 标准化面积

河北省自然科学基金河北省卫健委跟踪项目河北省医学科学研究课题

A2019208336GZ202005020200082

2024

临床放射学杂志
黄石市医学科技情报所

临床放射学杂志

CSTPCD北大核心
影响因子:0.872
ISSN:1001-9324
年,卷(期):2024.43(3)
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