Objective To evaluate the values of diagnosing and distinguishing benign and malignant single nodules in thyroid gland with 640-slice spiral CT.Methods The CT manifestations of thyroid gland's single nodules in 48 patients were retrospectively analyzed,including 28 crestoid carcinoma of the thyroid gland and 20 benign thyroid nodules(16 nodu-lar goiter and 4 thyroid adenomas).All cases were proved by operation and histopathology.The observed indexes were as:(1)Thyroid general condition:volume,shape and density.(2)The CT finding of nodules:size,location,densities(homoge-neity or unhomogeneity,calcification),margin(the cookie bite sign),enhancing condition(enhancing mode,strength,clea-rer margin and smaller than non-enhancing).(3)The organ changing around thyroid gland:tracheal displacement,lymphatic metastasis.Results The size,margin(the cookie bite sign),enhancing strength and Thyroid general condition had markedly statistical significance between benign and malignant single nodules in thyroid gland(P<0.05).The location of nodules,density and tracheal displacement hadn't statistical significance between benign and malignant single nodules in thyroid gland(P>0.05),but lymphatic metastasis justly was seen in crestoid carcinoma of the thyroid gland.Conclusion The CT manifestations between benign and malignant single nodules of thyroid gland appeared overlapping,but accurately qualitative diagnosing could be obtained by means of observing carefully typical and atypical CT finding,combining thyroid general condition and lymphatic metastasis.
Thyroid glandSingle nodulesCrestoid carcinoma of the thyroid glandBenign thyroid nodulesCT di-agnosis and differentiating
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