Objective To analyze the MR and CT imaging manifestations of central nervous system leukemia(CNSL).Methods The MR and CT imaging data of patients with CNSL between January 2010 and October 2021 were analyzed ret-rospectively,who underwent head enhanced MR scanning.Results There were 41 patients.MR was positive in 32 cases(78.0％),of which 27 cases(65.9％)were intracranial infiltration,including 14 cases(34.1％)of cranial nerve thick-ening,13 cases(31.7％)of meningeal enhancement or space occupying,4 cases(9.8％)of brain parenchyma occupation and 1 case(2.4％)of intracerebral ventricular occupation.6 cases(14.6％)of cranial nerve thickening were accompa-nied by space occupying in areas of cranial nerves.Among the patients with meningeal enhancement or space occupying,there were 7 cases(17.1％)with leptomeningeal enhancement,2 cases(4.9％)with dural enhancement,and 5 cases(12.2％)with dural space occupying.Head CT was performed in 20 cases(48.8％)in the same period,and 9 cases were positive(45％).Among them,7 cases showed intracranial infiltrative lesions,all of which were space occupying lesions with homogeneous slightly high-density shadows.There were 9 cases(33.3％)of missed diagnosis of intracranial infiltrating le-sions on MR plain scanning and 7 cases(50.0％)of missed diagnosis on CT.Conclusion The imaging manifestations of CNSL include cranial nerve infiltration,meningeal infiltration,brain parenchyma and intraventricular infiltration and so on.Enhanced MR is of great value in diagnosis,and plain CT has a high detection rate only for space occupying lesions.
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