Objective To analyze the X-ray and MRI characteristics of different luminal breast cancers,and to evaluate their predictive value for sentinel lymph node(SLN)metastasis in breast cancer.Methods Clinical data of 88 patients with luminal breast cancer admitted between January 2020 and April 2022 were retrospectively analyzed.Patients were clas-sified into Luminal A and Luminal B according to molecular typing.MRI and molybdenum target X-ray images were per-formed.Diffusion parameters including apparent diffusion coefficient(ADC),perfusion fraction(f),maximum slope of in-crease(MSI),and true diffusion coefficient(D)were measured using post-processing techniques.Then receiver operating characteristic curve was plotted to evaluate the effectiveness of each parameter in the differential diagnosis of breast cancers.Results No statistical difference was reported in ADC,f,and MSI values between Luminal A type and Luminal B type(P＞0.05),whereas Luminal A type patients yielded a higher D values and higher SER values than Luminal B type patients,with statistical difference(P＜0.05).The areas under the curve(AUCs)of MRI-D,MRI-SER,MRI-D/SER,and molybde-num target X-ray in the diagnosis of Luminal A type were 0.869,0.882,0.915,and 0.911,respectively.The AUCs of MRI-D,MRI-SER,MRI-D/SER,and molybdenum target X-ray in the diagnosis of SLN metastasis were 0.885,0.953,0.979,and 0.966.Conclusion MRI-D,MRI-SER,MRI-D/SER and molybdenum target X-ray have high accuracy in dif-ferentiating breast cancer subtypes and predicting SLN metastasis.
Luminal subtypesBreast cancerMRIMolybdenum target X-ray imagesSentinel lymph node metas-tasis in breast cancer
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