Objective To explore the prognostic value of proximal lesions based on coronary CT angiography(CCTA)in non-obstructive coronary artery disease(NOCAD).Methods Finally 3359 patients with clinically confirmed or sus-pected coronary artery disease(CAD)in our hospital from November 2017 to December 2019 were continuous collected.Univariate and Multivariate Cox regression models were used to explore the risk factors of MACE.Results The mean age of patients in the NOCAD group was higher than that in no CAD group,the proportion of men in the NOCAD group was higher than that in no CAD group,and the proportion of smoking,drinking,hypertension and diabetes was higher than that in no CAD group(P＜0.001).The mean age and proportion of people with hypertension in NOCAD with proximal lesions group was higher than that in NOCAD without proximal lesions group(P＜0.05).There was no significant difference be-tween the two groups in age,gender,smoking,drinking and hypertension(P＞0.05).154 patients occurred MACE in NO-CAD with proximal lesions group.The incidence rate of MACE was 10.58％and the annual incidence rate of MACE was 2.8％(95％CI:2.4％-3.3％).The HR of NOCAD with proximal lesions group was 1.45(95％CI:1.09-1.91,P=0.010),when no CAD was used as reference.The HR of NOCAD without proximal lesions group was 1.01(95％CI:0.67-1.78,P=0.735),when no CAD was used as reference.Conclusion The proximal lesions of NOCAD based on CCTA were 1.45 times higher than those of no CAD.The plaque location based on CCTA may provide additional prognostic value for MACE risk prediction in patients with NOCAD.
NETL
NSTL
万方数据
