Objective The aim of this study was to investigate the relationship between epicardial adipose tissue volume(EAT)and the risk and load level of frequent premature ventricular complexes(PVC).Methods Retrospective analysis of 80 patients with frequent PVCs and 160 patients without PVCs who underwent computed tomography at the First Affiliated Hospital of Zhengzhou University between October 2020 and December 2021.The evaluation criteria of the 1∶1 propensity to match score(PSM)adjusted analysis were applied.Multifactorial logistic regression was used to analyze the risk factors for the occurrence of frequent PVCs.The relationship between EAT volume and the load level of frequent PVCs was ana-lyzed according to the median number of patients with frequent PVCs divided into a high PVCs burden group and a low PVCs burden group.Results In both the unadjusted and PSM-adjusted cohorts,EAT volume was significantly greater in patients with frequent PVCs than in controls(both P＜0.001).Multifactorial logistic regression analysis showed that EAT volume was an independent risk factor for frequent PVCs.(all P＜0.001)In patients with frequent PVC,EAT volume was higher in the high PVCs burden group.Conclusion Patients with frequent PVCs have larger EAT volumes compared with controls,and EAT volume is an important independent predictor of freguent PVCs.EAT volume,as an easily measured quantitative index,provides a new insight to differentiate patients with frequent PVCs.
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