Preliminary Study on the Efficacy of PD-1 Antibody Combined with Antirotinib and 125I seed Chain Implantation in the Treatment of Perihilar Cholangiocarcinoma(Analysis of 3 Cases)
Objective To investigate the initial efficacy and safety of PD-1 antibody combined with antirotinib and 125I seed chain implantation in the treatment of perihilar cholangiocarcinoma.Methods Clinical data of 3 patients with peri-hilar cholangiocarcinoma admitted to our department from April to January 2021 were retrospectively analyzed.All of them were confirmed by pathology combined with laboratory examination and imaging examination.Under the guidance of DSA,percutaneous transhepatic cholangiography was performed,biliary stent and 125I particle drainage tube were inserted,and then regular treatment was performed with tirelizumab and anrotinib.Results All the three patients were successfully op-erated.Particle drainage tube effectively covered the diseased area of bile duct,and the disease conditions were effectively controlled after treatment with tiralizumab and anrotinib.Conclusion Tirelizumab combined with allotinib and 125I seed chain implantation is safe and effective in the treatment of perihilar cholangiocarcinoma.
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