Objective To explore the value of quantitative features of CT in the differential diagnosis of gastric stromal tumors(GST)with a diameter of less than 3 cm and heterotopic pancreas(HP).Methods The clinical information,path-ological findings and imaging data of 123 cases of GST and 57 cases of HP confirmed by surgical pathology in our hospital from January 2020 to February 2023 were retrospectively analyzed,and Chi-square test was used to compare the data Quali-tative parameters(gender,location,etc.)of patients in 2 groups were compared with quantitative parameters(age,artery ratio,etc.)of patients in 2 groups by t test of two independent samples.Binary logistic regression model was used to screen out independent predictors of GST and HP,and receiver operating characteristic(ROC)curve was used to analyze the diag-nostic efficacy of CT features in differentiating GST from HP.Results Compared with patients with mesenchymal tumor,ectopic pancreas patients were more male(63.2%vs.34.1%)and younger[(37.6±10.0)years vs.(57.4±10.0)years].The tumors were more located in gastric antrum(84.4%vs.61.5%),and the enhancement was uniform and signif-icantly enhanced.The focal components were mostly solid(89.5%vs.48.8%,53.9%vs.24.4%,94.7%vs.61.0%),the ratio of long diameter to short diameter(LD/SD ratio)was larger[(1.5±0.4)cm vs.(1.3±0.2)cm],arterial CT value was larger[(82.6±11.2)HU vs.(63.4±11.7)HU],arterial ratio and arterial enhancement rate were larger[(220.9±58.4)%vs.(186.9±49.9)%,(120.9+58.4)%vs(86.9+49.9)%],the difference had statistical significance(P<0.05).Binary logistic regression analysis showed that the independent predictors of diagnosis of GST and HP included gender,age,LD/SD ratio,and arterial enhancement rate.The optimal cut-offs of LD/SD ratio and arterial en-hancement rate were 1.23 and 0.42,respectively,which could be used as reference indicators for the differentiation of the two.When combined with gender,age,long/short diameter and arterial enhancement rate,the ROC curve analysis showed that the area under the curve was 0.959,and the diagnostic sensitivity and specificity were 87.7%and 91.1%respective-ly.ROC analysis results of independent predictors and combined diagnosis model showed that the area under the curve of gender,age,LD/SD ratio,arterial enhancement rate and combined diagnosis model were 0.645,0.912,0.659,0.663 and 0.959,respectively,indicating that combined diagnosis model had higher diagnostic efficacy(P<0.001).Conclusion CT characteristics such as sex,age,LD/SD ratio,and arterial enhancement rate can be used to distinguish gastric stromal tumor from heterotopic pancreas.