Objective Mitral regurgitation after myocardial infarction(MI)leads to a significant increase in the risk of irreversible congestive heart failure and long-term mortality in patients,especially in those with moderate to severe mitral re-gurgitation,thus determining the predictors of mitral regurgitation in MI patients is of great clinical value.The purpose of this study is to explore the influencing factors of mitral regurgitation after myocardial infarction with cardiovascular magnetic res-onance(CMR).Methods Between July 2015 and March 2023,MI patients at admission were included in this study.Ac-cording to the follow-up results,the study populationts were divided into non-mitral regurgitation group,mild mitral regurgi-tation group and moderate to severe mitral regurgitation group.CMR parameters,including global longitudinal strain(GLS),global circumferential strain(GCS),global radial strain(GRS),left ventricular ejection fraction(LVEF),left ventricular end-diastolic volume index(LVEDVI),left ventricular end-systolic volume index(LVESVI),and infarction volume,were obtained by software CVI 42.Multivariate analyses were performed to identify influencing factors in the development of mi-tral regurgitation.Results A total of 112 participants,36 in non-mitral regurgitation group,59 in mild mitral regurgitation group and 31 moderate to severe mitral regurgitation group were included.There were significant differences between the GLS、GCS、GRS、LVEF、LVEDVI、LVESVI(P<0.05)among three groups,while there was no significant differences in in-farction volume among three groups.Multivariate logistic regression analysis showed that GCS and LVESVI were influencing factors of mitral regurgitation after MI(P<0.05).Conclusion The LV strain combined with LVESVI can effectively re-flect the effect of LV remodeling on mitral regurgitation after MI.