首页|延年九转法对慢性疲劳综合征睡眠障碍的静息态功能磁共振成像研究

延年九转法对慢性疲劳综合征睡眠障碍的静息态功能磁共振成像研究

Study on Resting State Functional Magnetic Resonance Imaging in Intervention of Sleep Disorder in Chronic Fatigue Syndrome by Prolong Life With Nine Turn Method(Yan Nian Jiu Zhuan)Qigong

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目的 基于功能磁共振成像(fMRI)低频振幅(ALFF)探讨延年九转法对慢性疲劳综合征(CFS)睡眠障碍患者脑部神经元自发活动的调节作用.方法 选取30例自愿参与fMRI检测的CFS患者随机分配到延年九转法组和认知行为组,分别于12周干预前后进行头部静息态功能磁共振成像(rs-fMRI)扫描,分析ALFF神经元活动强弱,并于12周后进行匹兹堡睡眠质量指数(PSQI)评分.结果 与认知行为组相比,延年九转法组在右侧前扣带回、右侧额上回ALFF值增强,在左侧枕中回、左侧颞中回、右侧枕中回、右侧枕上回ALFF值减弱(P＜0.001,FWE校正).与治疗前相比,延年九转法组左侧尾状核、左侧额上回、左侧中央前回ALFF值增强,左侧角回、右侧角回、左侧顶上回、右侧顶上回、右侧枕中回、左侧枕上回ALFF值降低(P＜0.001,FWE校正).临床疗效上,与治疗前相比,延年九转法干预后PSQI在主观睡眠质量、睡眠潜伏期、睡眠紊乱、白天功能紊乱和睡眠持续性分值具有统计学差异(P＜0.05).结论 延年九转法可改善CFS患者的临床症状,且存在脑功能区神经元活动异常,fMRI能对CFS疗效评估和判断提供一定的帮助.
Objective Based on the low frequency amplitude(ALFF)functional magnetic resonance technique,to ex-plore the mechanism of improving chronic fatigue syndrome(CFS)sleep disorders with the Yannian Jiuzhuan method.Methods Thirty CFS patients who voluntarily participated in the fMRI test were randomly assigned to the Nine Years Ex-tension Method Group and the Cognitive Behavior Group,and the PSQI scale measurement and resting functional magnetic resonance(fMRI)scan of the head were performed around 12 weeks.The scale score and the strength of ALFF neuron ac-tivity were analyzed.Results Compared with the cognitive behavior group,the right anterior cingulate gyrus and right su-perior frontal gyrus ALFF in the Gongfa group were enhanced;left middle occipital gyrus,right middle occipital gyrus,left middle temporal gyrus,right superior occipital gyrus ALFF activity weakened.Compared with before the test,the left caudate nucleus,left superior frontal gyrus,and left central anterior gyrus ALFF were enhanced in the Gongfa group;ALFF decreased in the right corner gyrus and the right top gyrus.Conclusion The Yannian Jiuzhuan method can effectively treat sleep disorders in CFS patients.The increased excitability of the left superior frontal gyrus and the left central anterior gyrus may be a possible mechanism for the Yannian Jiuzhuan method to improve sleep disorders in CFS patients.

Nine-turn method for prolonging lifeSkillsSleepFunctional magnetic resonance imagingPSQI

谢芳芳、谢超群、岳虹妤、马健文、崔家禾、韩浩天、尤艳利、姚斐

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201203 上海中医药大学针灸推拿学院

200433 上海长海医院

延年九转法 功法 睡眠 功能磁共振成像 PSQI

国家自然科学基金青年基金国家自然科学基金面上项目国家重点研发计划中医药现代化研究重点专项(十三五)军队后勤科研重点项目(1226工程科技重点项目)(2017)

82105038823746102017YFC1703301BWS17J028

2024

临床放射学杂志
黄石市医学科技情报所

临床放射学杂志

CSTPCD北大核心
影响因子：0.872
ISSN：1001-9324
年,卷(期)：2024.43(6)
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