Objective To explore the correlation between left ventricular mechanical dispersion(LVMD)and QTc(corrected QT interval)of ECG parameters in patients with myocardial infarction(MI)based on cardiac magnetic resonance tissue feature tracking(CMR-FT).Methods According to the followed-up,MI diagnosed by clinical and CMR were en-rolled and divided into two groups according to the presence or absence of MACEs during follow-up.Left ventricular func-tional parameters,including left ventricular ejection fraction(LVEF),left ventricular end-diastolic volume(LVEDV),left ventricular end-systolic volume(LVESV),and LVMD derived from strain parameter were obtained by software CVI 42.QTc interval obtained by ECG,these parameters were acquired within the same week.Independent samples t-test,Mann-Whitney U test,and x2 test were used to compare the baseline data,left ventricular function,and strain parameters between the two groups.Spearman correlation analysis was applied to analyze the correlation between LVMD and QTc interval,long QTc interval(QTc interval＞440 ms),and regular QTc interval,and further explored the correlation between LVMD and QTc interval in the MACE group and without MACE group in MI patients.Results A total of 169 patients with MI were included,with a median follow-up of 25 months,56 in the MACE group and 113 in the without MACE group.Significant differences were observed in age,LVEF,QTc interval,and LVMD between the two groups(all P＜0.05).Spearman correla-tion analysis showed that LVMD was positively associated with QTc interval(rs=0.590,P＜0.001),long QTc interval(rs=0.542,P＜0.001),and regular QTc interval(rs=0.249,P=0.033).The correlation between LVMD and QTc interval was higher in patients in the MACE group(rs=0.544,P＜0.001)than in the without MACE group(rs=0.358,P=0.001).Conclusion LVMD evaluated by CMR was positively correlated with the electrocardiographic parameters QTc in-terval and long QTc interval.The correlation between LVMD and QTc interval was more significant in MI patients with long QTc interval.This suggests that LVMD increases with the prolongation of QTc interval and reflects the micro-electrophysio-logical alterations of myocardial.The correlation between LVMD and QTc interval was higher in the MACE group and more significant than in the without MACE group.This suggests that the risk of MACE may be associated with increased LVMD and prolonged QTc interval,which contributes to a deeper awareness of the risk stratification of MACE in MI patients.
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