Objective To investigate the effect of traditional cardiovascular risk factors such as age and gender on PCAT in people without coronary atherosclerosis.Methods A total of 526 subjects without coronary atherosclerosis con-firmed by CCTA examination were retrospectively included.PCAT volumes and FAI were measured at 40 mm proximal to the LAD and LCX and 10 mm to 50 mm proximal to the RCA,then the effect of each cardiovascular risk factor on PCAT was analyzed.Results(1)Multivariate logistic regression showed that gender,age and BMI were independent influences on PCAT-FAI and volume,and the symptoms of precordial discomfort were independently associated with PCAT volume.(2)PCAT-FAI and volume were both higher in men than in women(P＜0.05).(3)There was a statistically significant differ-ence between the PCAT parameters in the female youth group and the middle-aged and elderly groups(P＜0.01).(4)A-nalysis of different coronary trunks showed that there was a statistically significant difference in PCAT volume between two comparisons of all three coronary trunks(P＜0.001).PCAT volume was highest in RCA and lowest in LCX;LCX was highest in PCAT-FAI analysis,and the FAI values of LCX differed statistically significantly from both LAD and RCA(P＜0.001).Conclusion In non-atherosclerosis population,PCAT related parameters varied among different genders,ages and coronary branches,suggesting that the normal reference intervals for PCAT volume and FAI should be set separately considering relevant influencing factors.
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