Feasibility Study of Dual Layer Spectral Detector CT Derived Virtual Non-Contrast Images Substitute for True Non-Contrast Images in Evaluating Colorectal Cancer
Objective To explore the value of virtual non-contrast(VNC)derived from dual layer spectral detector CT(SDCT)in the diagnosis of colorectal cancer.Methods The imaging data of 52 patients with colorectal cancer were col-lected in our hospital.The CT value,SD,SNR and CNR of the colorectal cancer lesions,abdominal aorta,paravertebral muscle/gluteus maximus,subcutaneous fat were evaluated among TNC,VNC-A,VNC-V,VNC-D images,and the four groups subjective image quality were assessed.Results There were no significant differences in the CT values of lesions and pa-ravertebral muscle/gluteus maximus among four groups images(all P＞0.05),while there were significant differences in CT values of abdominal aorta and subcutaneous fat(all P＜0.05).Image noise of all tissues was significantly lower in three-phase VNC images than that in TNC images.Meanwhile,the SNR of lesions and abdominal aorta was higher than that of TNC(P＜0.05).All the four groups images could meet the diagnostic requirements,and the consistency of subjective e-valuation by two observers was good.The radiation dose can reduce by about 22.39％using"VNC+enhanced CT"proto-col.Conclusion The image quality of VNC derived from dual layer spectral detector CT is closer to that of TNC in evalu-ating colorectal cancer and the radiation dose was lower.
Colorectal cancerTomography,X-ray computedVirtual non-contrastQuality control
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