Objective To investigate the value of apparent diffusion coefficient(ADC)and quantitative dynamic con-trast-enhanced magnetic resonance imaging(qDCE-MRI)in grading cervical carcinoma.Methods Imaging data of 95 patients who were newly diagnosed with cervical carcinoma proved by surgical pathology were retrospectively analyzed in Sun Yat-Sen memorial hospital from July 2017 to December 2021.All patients underwent conventional MRI,diffusion weighted imaging and qDCE-MRI before surgery.The difference and correlation of Ktrans,Kep,Ve,Vp and ADC value among different histopathologic grades were analyzed.The efficacy of these parameters in predicting G1/2 and G3 cervical carcinoma were also analyzed.Results Ktrans and Kep correlated positively with tumor's histopathologic grade(r=0.323,P=0.001 and r=0.455,P＜0.001).There were statistical differences for Ktrans and Kep between G3 and G1/2 tumors(Z=-2.769,P=0.006 and Z=-4.321,P＜0.001).The sensitivity,specificity and accuracy of Ktrans in predicting G3 and G1/2 tumors were 60.8％,72.7％and 66.3％,respectively.The sensitivity,specificity and accuracy of Kep in predicting G3 and G1/2 tumors were 82.4％,63.6％and 73.7％,respectively.Conclusion Ktrans and Kep correlated positively with pathological grades of cervical carcinoma and both of them can be used to differentiate G3 tumors from G1/2 tumors.
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