Objective To analyze the difference of bone mineral density between non-Chronic obstructive pulmonary disease(COPD)patients and different grades of COPD patients.To analyze the correlation between bone mineral density and COPD severity in COPD patients.Methods A total of 171 patients who underwent lung function examination,and chest gemstone spectral imaging examination in our hospital from January 202 1 to September 2022 were collected.Pulmona-ry function test results,including FEV1/FVC％and FEVI％pred,were recorded.Patients were divided into group A(non-COPD),group B(mild COPD),group C(moderate COPD),group D(severe COPD),and group E(extremely severe COPD)according to the diagnostic guidelines for COPD.BMD spectral parameters,including HAP(water),calcium(wa-ter),HAP(fat)and λ,were measured in the middle thoracic vertebra(T5-8)of the patient using GE AW 4.7 post-pro-cessing workstation,and the mean value of the middle thoracic vertebra was obtained.The differences of bone mineral den-sity energy spectrum parameters among 5 groups were compared.The correlation between bone mineral density energy spec-trum parameters and lung function parameters in COPD patients was analyzed.Results HAP(water),Calcium(water),HAP(fat)and λof middle thoracic vertebra were significantly different among 5 groups(all P＜0.001).Multiple compari-son results show that,HAP(water),Calcium(water),HAP(fat)and λ were as follows:group A＞group D and E,group B＞group D and E,group C＞group D and E(all P＞0.05).HAP(water),Calcium(water),HAP(fat)and λ were gener-ally correlated with FEV1/FVC％(all rs＜0.6,P＞0.001),and were strongly positively correlated with FEV1％pred(all rs＞0.6,P＜0.001).Conclusion The aggravation of pulmonary function impairment in COPD patients,especially the severity and above level,can lead to the decrease of bone density.
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