Objective To explore the correlation between hemoglobin,serum uric acid and lumbar spine bone mineral density(BMD)in middle-aged and elderly male physical examination population based on Quantitative CT(QCT).Methods A total of 3611 middle-aged and elderly male physical examination population who underwent chest CT com-bined with QCT examination in the Health Management Discipline of Henan Provincial People's Hospital from January 2022 to February 2023 were selected as the study subjects,and their age,body mass index(BMI),hemoglobin,serum uric acid and blood lipid indexes were collected,and lumbar spine BMD was measured by QCT.According to the result of BMD,the subjects were divided into normal bone mass group(＞120 mg/cm3),reduced bone mass group(80～120 mg/cm3)and osteoporosis group(＜80 mg/cm3).Univariate ANOVA,Pearson correlation and multivariate binary logistic regression model were used to analyze the correlation between hemoglobin,serum uric acid and lumbar spine BMD.Results There were significant differences in age,BMI,hemoglobin,total cholesterol,triglycerides,low-density lipoprotein and serum uric acid between different lumbar spine BMD groups(P＜0.05).The results of Pearson correlation analysis showed that BMI,hemoglobin,total cholesterol,triglycerides,low-density lipoprotein and serum uric acid were positively correlated with lumbar spine BMD(r=0.049,0.162,0.090,0.066,0.077,0.064,P＜0.05),but age was negatively correlated with lumbar spine BMD(r=-0.410,P＜0.001).The results of multivariate binary Logistic regression showed that hemoglobin and slightly elevated serum uric acid were the protective factors for osteoporosis in middle-aged and elderly men after adjusting for other variables(OR=0.978,OR95％CI:0.969～0.987,OR=0.998,OR95％CI:0.997～1.000).Conclusion In middle-aged and elderly male physical examination population,hemoglobin and serum uric acid are correlated with lumbar spine BMD,and hemoglobin and serum uric acid are the influencing factors of osteoporosis in middle-aged and elderly male physical examination population.
Quantitative CTLumbar spine bone mineral densityHemoglobinSerum uric acidBlood lipid inde-xesCorrelation analysis
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