Objective To explore the differences in MRI features between breast lobular carcinoma and ductal carcino-ma with non-mass enhancement(NME)on dynamic contrast-enhanced MRI(DCE-MRI),and to compare and analyze path-ological related indexes.Methods Imaging and pathological data of 92 breast cancer patients presenting with NME on MRI were retrospectively analyzed.They were divided into two groups according to the pathological results,including 41 ca-ses of lobular carcinoma and 51 cases of ductal carcinoma.Chi-Squared or Fisher exact test and Mann-Whitney U test were used to compare and analyze the imaging and pathological data of the two groups of patients,including age,location and size of lesions,type of mammary gland,multifoci,peritumoral edema,distribution and internal enhancement features of NME,es-trogen receptor(ER),progesterone receptor(PR),human epidermal growth factor receptor-2(HER-2)status,lymph node metastasis,etc.Results lobular carcinoma and ductal carcinoma showed statistical differences in the maximum transverse diameter(P=0.010),enhancing strands(P=0.038),NME morphological distribution(P=0.042),NME enhancement features(P＜0.001),PR(P=0.047),HER-2(P=0.004),Ki-67(P=0.011)and lymph node metastasis(P=0.033).There were no significant differences in lesion location(P=0.363),gland type(P=0.293),multifoci(P=0.798),peritumoral edema(P=0.518)and ER(P=0.162)between the two groups(P＞0.05).Conclusion There are certain differences in MRI features and pathological related indicators between breast lobular carcinoma and ductal car-cinoma with NME.MRI can provide assistance for the pre-treatment diagnosis of lobular carcinoma and ductal carcinoma with NME.
Breast cancerMagnetic resonance imagingNon-mass enhancementPathological featuresLobular carcinoma of breast
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