The Study on Characteristics and Sex Differences of Coronary Atherosclerosis in Asymptomatic High Risk Population for Coronary Artery Disease Using Coronary Computed Tomography Angiography
Objective Investigating coronary atherosclerosis(CAS)characteristics and sex differences in asymptomatic high risk population for coronary artery disease(CAD).Methods Total of 774 asymptomatic individuals with more than 4 high risk factors for CAD underwent coronary computed tomography angiography(CCTA)for suspected CAD and final 623 individuals were involved for analysis.The CAS,Coronary Involvement Score(SIS)and Coronary Artery Disease-Report and Data System(CAD-RADS)Stenosis score(St.S)were compared between male and female patients.Results ①In the high-risk population for CAD,the top factors related with CAS were hypertension(HYP),HYP duration(HYPD)and high level triglyceride.②There was no significant difference in the incidence of CAS between sexes,but the average SIS and SIS ≥4 were higher in males than in females.③Although there was no difference in average St.S between different sex,there were more females with St.S ≥ 3 than males.Conclusion There was no sex difference in the incidence rate of CAS among asymptomatic CAD high-risk individuals,but there were significant differences in the high-risk characteristics of CAS,the featuresare helpful to the precise prevention of CAD.