无症状冠状动脉粥样硬化性心脏病高危人群CCTA特征及性别间差异研究
The Study on Characteristics and Sex Differences of Coronary Atherosclerosis in Asymptomatic High Risk Population for Coronary Artery Disease Using Coronary Computed Tomography Angiography
张帆 1赵林芬 2李涛 3徐崧 4张晶 3张兴华 3王新疆 5杨立6
作者信息
- 1. 572013 中国人民解放军总医院海南医院放射诊断科;100853 中国人民解放军总医院第一医学中心放射科
- 2. 100853 中国人民解放军总医院第一医学中心放射科;213161 南京中医药大学附属武进中医医院放射科
- 3. 100853 中国人民解放军总医院第一医学中心放射科
- 4. 572013 中国人民解放军总医院海南医院放射诊断科
- 5. 100853 解放军总医院第二医学中心放射科
- 6. 100853 中国人民解放军总医院第一医学中心放射科;100853 解放军总医院第二医学中心放射科
- 折叠
摘要
目的 探讨无症状冠状动脉粥样硬化性心脏病(CAD)高危人群的冠状动脉CT成像(CCTA)特征及性别间差异.方法 搜集2019年因有CAD高危因素4项以上并行CCTA检查的无症状人群774例,记录CAD高危因素和冠状动脉粥样硬化(CAS)及其高危征象,最后纳入符合标准的受试者623例,分析CCTA显示的CAS特征及在不同性别人群之间有无差异;结果 高危人群中,对CAS发生影响最为突出的因素为高血压(HYP)、高血压病程(HYPD)和甘油三酯(TG)水平;不同性别CAS发生率并无明显差异,平均冠状动脉受累积分(SIS)及高危特征SIS≥4男性高于女性;CAD报告狭窄分级系统(CAD-RADS)积分St.S＜3性别间并无明显差异,但高危特征St.S 3女性多于男性.结论 CAD高危人群CAS发生率性别间并无明显差异,但SIS＜4及SIS≥4和St.S≥3性别间存在显著差异,在对CAD精准预防中应予关注.
Abstract
Objective Investigating coronary atherosclerosis(CAS)characteristics and sex differences in asymptomatic high risk population for coronary artery disease(CAD).Methods Total of 774 asymptomatic individuals with more than 4 high risk factors for CAD underwent coronary computed tomography angiography(CCTA)for suspected CAD and final 623 individuals were involved for analysis.The CAS,Coronary Involvement Score(SIS)and Coronary Artery Disease-Report and Data System(CAD-RADS)Stenosis score(St.S)were compared between male and female patients.Results ①In the high-risk population for CAD,the top factors related with CAS were hypertension(HYP),HYP duration(HYPD)and high level triglyceride.②There was no significant difference in the incidence of CAS between sexes,but the average SIS and SIS ≥4 were higher in males than in females.③Although there was no difference in average St.S between different sex,there were more females with St.S ≥ 3 than males.Conclusion There was no sex difference in the incidence rate of CAS among asymptomatic CAD high-risk individuals,but there were significant differences in the high-risk characteristics of CAS,the featuresare helpful to the precise prevention of CAD.
关键词
无症状高危人群/冠状动脉粥样硬化性心脏病/糖尿病/冠状动脉计算机断层成像Key words
Asymptomatic individual/Coronary artery disease/Diabetes mellitus/Coronary computed tomography angiography引用本文复制引用
基金项目
国家自然科学基金面上项目()
三亚市医疗卫生科技创新项目计划资助项目(81371547)
三亚市医疗卫生科技创新项目计划资助项目(2014YW37)
出版年
2024
NETL
NSTL
万方数据