Objective Quantitative CT(QCT)was applied to measure liver/abdominal fat and lumbar bone mineral density to explore their correlation with thyroid hormone levels in male and female gender groups,respectively,and to evalu-ate the overall efficacy of the same by using factor analysis and R-lingual to draw correlation heatmaps and Receiver Operat-ing Characteristic(ROC)curves,and calculate the Area Under Curve(AUC).Methods 265 health checkups in our physical examination center were divided into two groups according to gender,quantitative CT was applied to measure liver/abdominal fat and lumbar bone mineral density,and thyroid hormone values were collected,and statistical software was ap-plied to analyze the correlation,and the results of the analyses were visualized.Results In the male group,there was a negative correlation between TT4 and FT4 and liver fat(TT4:r=-0.164,P=0.045;FT4:r=-0.239,P=0.003);in the female group,TSH correlated with liver fat(r=0.203,P=0.03),and there was a correlation between FT3 and mean subcutaneous area of fat(SAT)(r=0.223,P=0.017).Factor analysis indicated that combining thyroid hormone,liver/abdominal fat,and bone density indices into four common factors contributed 68.06％and 65.85％cumulatively in the male and female groups,respectively.The AUC of TSH to lumbar spine bone density was 0.717 in the male group,and the AUC of TSH to liver fat was 0.722 in the female group,with Yoden indices of 0.551 and 0.384,respectively.Conclusion Thyroid hormone levels and liver fat/abdominal fat in both male and female groups showed different degrees of correla-tion,and the combination of thyroid hormone indexes can improve the overall judgment efficacy of fatty liver,obesity and os-teoporosis to a certain extent..
Quantitative computed tomographyLiver/Abdominal fatLumbar bone mineral densityThyroid hor-mones
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