Objective To explore the value of CT and enhanced CT after direct lymphangiography in diagnosing chylo-thorax.Methods The clinical and imaging data of 16 patients diagnosed with chylothorax from July 1,2011 to June 30,2023 were retrospectively analyzed,and all of them underwent post-direct lymphangiography CT and CT-enhanced examina-tion.Results A large number of intrathoracic abnormalities could be seen on post-direct lymphangiography CT and CT enhancement,including abnormal contrast distribution,lung abnormalities,pleural abnormalities,mediastinal abnormalities,and bone abnormalities;solid lung lesions could be seen in 6 patients,lobular septal thickening in 2 patients,bronchial vas-cular bundles thickening in 5 patients,pleural thickening in 4 patients,and different degrees of bone destruction and hypo-density of thoracic vertebrae and ribs,and mediastinal enhancement could be seen in 4 patients.Mediastinal enhancement was seen in 4 patients.Conclusion Direct lymphangiography followed by CT and enhanced CT can clarify the character-istics of chest lesions,which is valuable for the diagnosis of chylothorax.