Objective To explore the MSCT,MRI and 18F-FDG PET/CT imaging manifestations and pathological basis of collecting duct carcinoma(CDC),so as to deepen the imaging understanding of this disease and improve the accuracy of diagnosis.Methods The data of 15 cases of renal collecting duct carcinoma confirmed by surgery and pathology were ret-rospectively analyzed.All of patients underwent multi-phase enhanced CT scans,of which 3 cases received enhanced MRI scans,and 3 received PET/CT scans.Summarizing the imaging manifestations and discussing the related pathological basis by comparing the imaging with pathology and reviewing literature.Results 8 cases of lesions were located in the left kid-ney,6 cases were in the right kidney,l case had left kidney CDC complicated with clear cell carcinoma of the right kidney,among which 12 cases were solid and 3 cases were cystic solid.5 cases mainly involved the renal medulla area,and the renal contour changes were not obvious.4 cases bulged out of the renal capsule or invaded the renal fascia sac,4 cases invaded the renal pelvis,and 2 cases were extensively involved in the renal pelvis,parenchyma and renal fascia sac.9 cases showed enlarged renal hilum and/or retroperitoneal lymph nodes and invaded the perirenal fat space(60％,9/15 cases),renal ve-nous carcinoma thrombus was observed in 4 cases(26.7％,4/15 cases).MRI:3 lesions showed equal or slightly high sig-nal on T1WI,slightly low signal on T2WI,and obvious high signal on DWI with the average ADC value was 0.975 × 10-3 mm2/s.Enhanced scan tumor parenchyma showed light-to-moderate progressive enhancement and"canine staggered"char-acteristic were observed in 5 cases(33.3％,5/15 cases).PET/CT:high uptake of 18F-FDG in tumor parenchyma,and the average SUVmax value was 7.41.The pathological examination showed papillary and glandular arrangement of tumor cells,proliferation of fibrous tissue in the stroma and infiltration of inflammatory cells.Conclusion CT shows lesion location,size and morphology well,and dynamic enhancement can reflect the characteristics of blood supply.MRI shows clear fibrous components and cystic necrosis of tumor,18F-FDG PET/CT shows better for lymph node and systemic metastasis.The com-bined application of these three is more helpful to comprehensively reflect the pathological basis and biological characteris-tics of renal tubular carcinoma.
维普
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