Objective To investigate the Impact of Atorvastatin on Epicardial Adipose Tissue Volume(EATV),epi-cardial adipose tissueCT attenuation(EAT CT attenuation),and Post-Radiofrequency Catheter Ablation(RFCA)Recur-rence Rates in Atrial Fibrillation Patients Based on CT Imaging.Methods A retrospective analysis was conducted on data from 192 AF patients who underwent RFCA at Jinan Central Hospital between April 2020 and December 2022.Patients were divided into Group A(116 patients receiving atorvastatin)and Group B(76 patients not receiving atorvastatin)based on post-operative atorvastatin use.Both groups underwent left atrial appendage CT enhancement before and 6 months after the procedure,with EATV and EAT CT attenuation calculated using Siemens post-processing software.Results Six months post-operation,EATV and EAT CT attenuation were significantly reduced in Group A(EATV:(-4±15)ml vs.(1±12)ml,P=0.013;EAT CT attenuation:(-2±6)HU vs.(1±6)HU,P＜0.001).At 18 months of follow-up,the recurrence rate of AF in Group A was significantly lower than in Group B(20 cases vs 32 cases,P＜0.001).Univari-ate Cox regression analysis indicated that atorvastatin use and reduction in EATV were beneficial factors in reducing AF re-currence.After adjusting for age,gender,body mass index(BMI),and AF type,multivariate Cox regression analysis showed that atorvastatin significantly reduced the risk of recurrence[HR=0.522(0.289,0.944),P=0.003].Conclu-sion The use of atorvastatin is associated with a reduction in EATV and EAT CT attention in AF patients as observed through enhanced CT imaging and is linked to a lower recurrence rate after RFCA.These findings provide new insights for improving the prognosis of AF patients.
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