Objective To investigate the conventional MRI and multimodal MRI features of polymorphous low-grade neuroepithelial tumor of the young(PLNTY)to enrich our knowledge about this rare tumor type.Methods A retrospec-tive analysis of clinical and radiological data was conducted on five patients with surgically and pathologically confirmed PLNTY.All patients underwent enhanced MRI scans,with three of them receiving multimodal MRI,and one patient under-going head CT examination.Results The case series included three males and two females with a median age of 25 years.Four patients presented with epilepsy.Conventional MRI revealed that four tumors were located in the temporal lobe and one in the parietal lobe;the average maximum diameter was approximately 1.76 cm(ranging from 1.1 to 3.7 cm).Three cases exhibited the"salt and pepper"sign on T2WI,with calcifications,cystic changes,and varying degrees of en-hancement observed in three cases.Multimodal MRI demonstrated that none of the five cases showed diffusion restriction;susceptibility-weighted imaging(SWI)identified calcifications within the lesion in two cases;magnetic resonance spectros-copy(MRS)showed inversion of the NAA/Cho ratio;diffusion tensor imaging(DTI)revealed invasion or compression of white matter fiber tracts;and perfusion-weighted imaging(PWI)demonstrated a mild increase in perfusion within the lesion areas.Conclusion PLNTY predominantly affects young adults and are commonly located in the subcortical area of tempo-ral lobe,often accompanied by calcifications and cystic changes.The"salt and pepper"sign on T2WI may be a characteris-tic feature.Multimodal MRI indicates its nature as a kind of low-grade glioma.Pathological examination is essential for the diagnosis of PLNTY,but the aforementioned features can assist differential diagnosis.
Polymorphous low-grade neuroepithelial tumor of the youngMagnetic resonance imagingMR spectros-copyDiffusion weighted imagingPerfusion weighted imaging
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