Clinical detection and analysis of acquired cytomegalovirus infection in extremely preterm infants
Objective To analyze the clinical characteristics of acquired cytomegalovirus infection in extremely preterm infants.Meth-ods The detection results of cytomegalovirus related antibodies in serum samples from 1 072 newborns in the Department of Neonatolo-gy of our hospital from July 1,2023 to September 15,2023 were retrospectively analyzed.Results Among the 1 072 newborns,2 were diagnosed with acquired cytomegalovirus infection.The two newborns were extremely preterm infants(24-27+6 weeks of gestational age)and extremely low birth weight infants(750-999 g).They presented with thrombocytopenia as the initial manifestation.One case was a transfusion-acquired cytomegalovirus infection and the other was a breast milk-acquired cytomegalovirus infection.Conclusion In special populations such as extremely preterm infants,it is necessary to prevent transfusion-acquired cytomegalovirus infection during transfusion therapy,as well as breast milk-acquired cytomegalovirus infection.If necessary,pasteurization should be used before feed-ing.