超早产儿获得性巨细胞病毒感染的临床检测及分析
Clinical detection and analysis of acquired cytomegalovirus infection in extremely preterm infants
张燕 1张虹 1王彦云1
作者信息
- 1. 南京医科大学附属妇产医院/南京市妇幼保健院新生儿筛查中心,南京 210004
- 折叠
摘要
目的 探讨获得性巨细胞病毒感染在超早产儿中的临床应用价值.方法 回顾性分析本院新生儿科 2023 年 7 月 1 日至 9 月15 日送检的1 072 例新生儿血清样本的巨细胞病毒相关抗体检测结果.结果 1 072 例样本中有2 例患儿确诊获得性巨细胞病毒感染.该2 例患儿均为超早产儿(胎龄24～27+6周)、超低出生体重儿(750～999 g),均以血小板降低为首发表现,1例为输血获得性巨细胞病毒感染,另 1 例为母乳获得性巨细胞病毒感染.结论 在超早产儿这类特殊人群中,输血治疗时需警惕输血获得性巨细胞病毒感染,同时也要谨防母乳获得性巨细胞病毒感染,必要时经巴氏消毒后再喂养.
Abstract
Objective To analyze the clinical characteristics of acquired cytomegalovirus infection in extremely preterm infants.Meth-ods The detection results of cytomegalovirus related antibodies in serum samples from 1 072 newborns in the Department of Neonatolo-gy of our hospital from July 1,2023 to September 15,2023 were retrospectively analyzed.Results Among the 1 072 newborns,2 were diagnosed with acquired cytomegalovirus infection.The two newborns were extremely preterm infants(24-27+6 weeks of gestational age)and extremely low birth weight infants(750-999 g).They presented with thrombocytopenia as the initial manifestation.One case was a transfusion-acquired cytomegalovirus infection and the other was a breast milk-acquired cytomegalovirus infection.Conclusion In special populations such as extremely preterm infants,it is necessary to prevent transfusion-acquired cytomegalovirus infection during transfusion therapy,as well as breast milk-acquired cytomegalovirus infection.If necessary,pasteurization should be used before feed-ing.
关键词
巨细胞病毒/输血获得性巨细胞病毒感染/辐照红细胞/超早产儿/超低出生体重儿Key words
cytomegalovirus/transfusion-acquired cytomegalovirus infection/irradiated red cell/extremely preterm infant/extremely low birth weight infant引用本文复制引用
基金项目
南京市卫生局项目(YKK19118)
江苏省妇幼健康项目(F202161)
宿迁市卫生局项目(Z2021070)
出版年
2024
NETL
NSTL
万方数据